Status 2 Patients Had Poor Prognosis Without Mechanical Circulatory Support

Safety and Efficacy of Autologous Skeletal Myoblast Sheets (TCD-51073) for the Treatment of Severe Chronic Heart Failure Due to Ischemic Heart Disease

“…Hence, clinical outcomes of patients with chronic HF are now significantly better, but patients with severe chronic HF who do not respond well to standard drug therapies still have poor outcomes. 1 In addition, although patients with end-stage severe HF benefit from heart transplantation or left ventricular assist system (LVAS) implantation, 2 these procedures are indicated for only a limited number of such patients worldwide where the number of heart 992 SAWA Y et al…”

Novel Scoring System Using Cardiopulmonary Exercise Testing Predicts Prognosis in Heart Failure Patients Receiving Guideline-Directed Medical Therapy

“…All patients accomplished CPXT without any complication (maximal load, 75±35 W). The expiratory change ratio was 1.3±0.2 (range 1.1-1.6), and the Borg scale was 18±2 points (range [17][18][19][20].…”

Indication of Ventricular Assist Device Therapy in Patients with INTERMACS Profile 4–7

“…7) It is no wonder that patients dependent on inotrope infusion soon receive VAD therapy, but more surprisingly survival rates of those who are listed but ambulatory (4-year survival rate, 68%) are similar to the patients once dependent inotrope (4-year survival rate, 65%). This strongly suggests the powerful ability to save life by VAD therapy.…”