Statistical Study on Congenital Heart Disease

Jeong, Jun Ah; Kim, Young Mi; Lee, Ho Seok; Kwon, Tae Chan; Kang, Chin Moo

doi:10.4070/kcj.1989.19.1.89

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“…Atrial septal defect (ASD) is a common congenital heart defect that constitutes 7.5-10% of all congenital heart defects found in children, 1) 2) and is one of the most common congenital heart lesions presenting in adult life. 3) The hemodynamic mechanism of ASD is a left-to-right shunt, which induces a volume overload to the right ventricle (RV).…”

Section: Introductionmentioning

confidence: 99%

Segmental Analysis of Right Ventricular Longitudinal Deformation in Children before and after Percutaneous Closure of Atrial Septal Defect

Cho

et al. 2014

J Cardiovasc Ultrasound

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BackgroundThe aim of study is to identify the dependence of right ventricular (RV) free wall longitudinal deformation on ventricular loading through segmental approach in relatively large number of patients with atrial septal defect (ASD).MethodsPatients with ASD (n = 114) and age matched healthy children (n = 60) were echocardiographically examined the day before percutaneous device closure and within 24 hours afterwards. RV free wall deformation parameters, strain (є) and strain rate (SR), were analyzed in the apical (єA, SRA) and basal (єB, SRB) segments. Measured deformation parameters were adjusted for RV size (єAL, SRAL, єBL, SRBL) by multiplying by body surface area indexed RV longitudinal dimension. Regression analyses determined the relationships of these deformation parameters with RV loading parameters that were measured by catheterization.ResultsєBL and SRBL were not different between pre-closure patients and controls (p = 0.245, p = 0.866), and were decreased post-closure (p = 0.001, p = 0.018). Post-closure єBL was lower than in controls (p = 0.001). Pre-closure єAL and SRAL were higher than in controls (p = 0.001, p < 0.001), but decreased after closure (all p < 0.001). The pulmonary to systemic flow ratio was related to procedural differences of єBL (p = 0.017) and of SRBL (p = 0.019). RV end diastolic pressure was negatively related to post-closure єBL (p = 0.020) and post-closure SRBL (p = 0.012), and the procedural SRBL difference (p = 0.027).ConclusionThe longitudinal deformation of the RV basal segment is dependent and its remodeling is also dependent on volume loading in children with ASD.

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Section: Introductionmentioning

confidence: 99%

Segmental Analysis of Right Ventricular Longitudinal Deformation in Children before and after Percutaneous Closure of Atrial Septal Defect

Cho

et al. 2014

J Cardiovasc Ultrasound

View full text Add to dashboard Cite

show abstract

Statistical Study on Congenital Heart Disease

Cited by 1 publication

References 0 publications

Segmental Analysis of Right Ventricular Longitudinal Deformation in Children before and after Percutaneous Closure of Atrial Septal Defect

Segmental Analysis of Right Ventricular Longitudinal Deformation in Children before and after Percutaneous Closure of Atrial Septal Defect

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