Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008

Abstract

Since the 1960s, more than 20,000 compounds were discovered from marine organisms. In this paper we performed a quantitative analysis for the novel marine natural products reported between 1985 and 2008. The data was extracted mainly from the reviews of Faulkner and Blunt [1–26]. The organisms producing these marine natural products are divided into three major biological classes: marine microorganisms (including phytoplankton), marine algae and marine invertebrate. The marine natural products are divided into seven classes based on their chemical structure: terpenoids, steroids (including steroidal saponins), alkaloids, ethers (including ketals), phenols (including quinones), strigolactones, and peptides. The distribution and the temporal trend of these classes (biological classes and chemical structure classes) were investigated. We hope this article provides a comprehensive perspective on the research of marine natural products.

Thoughts and facts about antibiotics: Where we are now and where we are heading

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Antimicrobial Activity of Callyspongia Diffusa (Marine Sponge) Associated Endophytic Bacteria L Strains

“…Since 1974, when the first sponge-derived natural products become part of the pharmacopoeia (e. g., cytarabine and vidarabine), marine natural products have gained much research interest [6,7]. So far, over 20,000 natural products have been isolated and identified from various marine organisms [8].…”

Bioprospecting for bioactives from seaweeds: potential, obstacles and alternatives

“…A quantitative analysis of the natural products of marine organisms demonstrated that more than 20000 compounds have been isolated and that the vast majority correspond to terpenoids and alkaloids from marine invertebrates (Hu et al, 2011;Blunt et al, 2011). Considering marine macroalgae, the number of isolated compounds corresponds to 10% of the total, mainly obtained from red and brown species.…”

“…Considering marine macroalgae, the number of isolated compounds corresponds to 10% of the total, mainly obtained from red and brown species. Halogenated compounds have received remarkable attention, mainly due to their strong bioactivity (Hu et al, 2011).…”