Abstract:β-lactamase inhibitors are potent synergistic drugs to reverse the drug resistant populations to sensitive ones. The production of such commercially important compounds needs much consideration on its production from the source organism. In the present study, a marine Streptomyces derived β-lactamase inhibitory compound kalafungin was optimized under solid state fermentation conditions. This study intended to facilitate the production of β-lactamase inhibitor by applying statistical methods of optimizing the c… Show more
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