One of the key guidelines in the European waste management policy is the diversion of waste from landfills, preventing harmful effects on human health and the environment and ensuring that economically valuable waste materials are efficiently recycled and reused through proper management. The organic fraction of municipal waste is abundant and contains biodegradable ingredients such lignocellulose, starch, lipids, pectin, and proteins, making it suitable for biotechnological production. Taking into account that a large amount of organic waste is disposed of in landfills, within this work, the amount of organic waste disposed of in the landfill in Banja Luka was considered. Four simulation model scenarios of the integrated production of bioethanol and biogas are generated, and their process and economic aspects are discussed. In the first two modelled scenarios, the pretreatment conditions (1% sulfuric acid and a different neutralization agent) were varied, while in the other two, the share of the amount of raw material used for the production of bioethanol, i.e., biogas, was varied (split factor: 10–90%). The modelled plant, with a designed capacity of 6 tons/h of organic waste, is a significant bioethanol producer, generating 5,000,000 L/year. The profitability indicators, when examined, revealed that dedicating a portion of the organic municipal waste input exclusively to biogas production leads to decreased process efficiency. Based on the modeled process parameters, ethanol’s minimum feasible selling price is $0.6616 per liter, while regarding the composition of organic municipal waste, carbohydrates have the most significant impact on the viability of the process. The developed model represents an excellent basis for further development of this integrated bioprocess in such a way that it can be modified with new process parameters or economic or ecological indicators and used at all levels of bioprocess design. Additionally, the obtained sustainable integrated bioethanol and biogas production plant models could support forthcoming steps in municipal waste management by providing reliable data on the conditions under which the integrated process of bioethanol and biogas production would take place, as well as the technical feasibility and economic profitability of such organic municipal waste utilization.
