Statistical Model Based HPLC Analytical Method Adjustment Strategy to Adapt to Different Sets of Analytes in Complicated Samples

Abstract

The results demonstrated that the SMB-AMA strategy was able to develop HPLC methods rationally and rapidly in the adaption of different sets of analytes. Copyright © 2017 John Wiley & Sons, Ltd.

Systematic evaluation of Rutongshu oral liquid based on chromatographic fingerprinting and nontargeted metabolomic analysis

“…In recent years, the quality of herbal medicine as well as their related products have been evaluated adopting chromatographic fingerprinting which emphasizes the characteristics of overall sample composition [8][9][10]. Among the many techniques used to characterize chemical profiles including Fourier-transform infrared (FT-IR) [11][12][13], mass spectrometry (MS) [14][15][16], nuclear magnetic resonance (NMR) [17][18][19], gas chromatography (GC) [20][21][22], high performance thin layer chromatography (HPTLC) [23][24][25] and thin-layer chromatography (TLC) [26][27][28], ultra-high performance liquid chromatography (UHPLC) [29][30][31] and high-performance liquid chromatography (HPLC) [32][33][34] are the most popularly used approaches used for fingerprinting due to its high sensitivity, high selectivity and low cost [35,36].…”