Statistical method to evaluate clean-up procedures in polychlorinated biphenyl analysis

Pietrogrande, Maria Chiara; Ghedini, D.; Dondi, Francesco; Velada, G.

doi:10.1039/a800554k

Cited by 11 publications

(11 citation statements)

References 28 publications

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“…1c, solid line). The first signal shows some high peaks (peaks 14,15,18,19,20,22,24) indicating that such PCPs (diisobutyl phthalate, chlorophene, musk ketone, fluoranthene, pyrene, 2,49-DDD, and 4,49-DDD) are selectively eluted from the cartridge with higher recovery than that found for the other PCPs, as confirmed by the higher recovery % values computed for these compounds (Table 4, 2nd column).…”

Section: Evaluation Of the Elution Patternmentioning

confidence: 61%

“…Both the parameters A T and A m can be used to quantitatively calculate the content of the target PCPs in the sample: the total area A T expresses the total amount of compounds present in the mixture, while A m represents the mean amount of each compound present in the mixture [20]. composition related to specific experimental conditions of the SPE procedure.…”

Section: Application To Evaluate Spe Strategymentioning

confidence: 99%

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Signal processing to evaluate parameters affecting SPE for multi‐residue analysis of personal care products

Pietrogrande

Basaglia

Dondi

2009

J of Separation Science

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Original PaperSignal processing to evaluate parameters affecting SPE for multi-residue analysis of personal care products This paper discusses the development of a comprehensive method for the simultaneous analysis of personal care products (PCPs) based on SPE and GC-MS. The method was developed on 29 target compounds to represent PCPs belonging to different chemical classes: surfactants in detergents (alkyl benzenes), fragrances in cosmetics (nitro and polycyclic musks), antioxidants and preservatives (phenols), plasticizers (phthalates) displaying a wide range of volatility, polarity, water solubility. In addition to the conventional C 18 stationary phase, a surface modified styrene divinylbenzene polymeric phase (Strata TM X SPE cartridge) has been investigated as suitable for the simultaneous extraction of several PCPs with polar and non-polar characteristics. For both sorbents different solvent compositions and eluting conditions were tested and compared in order to achieve high extraction efficiency for as many sample components as possible. Comparison of the behavior of the two cartridges reveals that, overall, Strata-X provides better efficiency with extraction recovery higher than 70% for most of the PCPs investigated. The best results were obtained under the following operative conditions: an evaporation temperature of 408C, elution on Strata-X cartridge using a volume of 15 mL of ethyl acetate (EA) as solvent and operating with slow flow rate (-10 KPa). In addition to the conventional method based on peak integration, a chemometric approach based on the computation of the experimental autocovariance function (EACVF tot ) was applied to the complex GC-MS signal: the percentage recovery and information on peak abundance distribution can be evaluated for each procedure step. The PC-based signal processing proved very helpful in assisting the development of the analytical procedure, since it saves labor and time and increases result reliability in handling GC complex signals.

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Section: Evaluation Of the Elution Patternmentioning

confidence: 61%

Section: Application To Evaluate Spe Strategymentioning

confidence: 99%

Signal processing to evaluate parameters affecting SPE for multi‐residue analysis of personal care products

Pietrogrande

Basaglia

Dondi

2009

J of Separation Science

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“…In previous papers it has been demonstrated that a chemometric approach based on Fourier Analysis (FA) is a powerful tool for decoding complex chromatograms [13][14][15][16][17][18][19][20][21][22][23][24][25][26] : in particular, its power lies in its ability to magnify ordered retention patterns, if present in the chromatogram, and single them out from the ″disordered forest″ of the random peaks [17][18][19][20][21][22][23][24][25][26] . The procedure has been successfully applied to chromatograms obtained under temperature programming conditions [13][14][15][16][17][18][19][20][21][22][23][24] .…”

Section: Introductionmentioning

confidence: 99%

GC—MS in Space Research: Decoding Complex Isothermal Chromatograms Recovered from Space Missions

2004

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An analytical procedure is described to study GC-MS isothermal chromatograms simulating those recovered from space missions: in fact GC plays a predominant role in space missions devoted to characterizing the chemical composition of extra-terrestrial atmospheres. SIM (selected ion monitoring) detection was used for monitoring selected chemical classes: a simplified chromatogram can be obtained giving information on the chemical composition of the complex mixture. Since only isothermal GC chromatograms are allowed by flight constraints, a time axis transformation is required to make them homogeneous: i.e., constant retention increments for CH2 additions in terms of a homologous series. The order in the linearized chromatogram can be simply singled out with a chemometric approach based on the study of the Autocovariance Function (ACVF) computed on the digitized chromatogram: the plot of the experimental autocorrelation function (EACF) shows well-shaped peaks if constant interdistances are repeated in different regions of the chromatogram. The method was applied to standard mixtures representative of planetary atmospheres--hydrocarbons, nitriles and oxygenated compounds with between 3 and 12 carbon atoms--analyzed in flight simulating conditions. The coupling of the selectivity of SIM detection with the interpretation power of the EACF procedure proves to be a powerful tool for interpreting data recovered from space missions: the chemical composition of the mixture can be identified by handling the raw SIM chromatograms.

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“…The analysis of PCBs is very difficult and always analytically challenging as PCBs are usually present in trace or ultra‐trace amounts and tend to be adsorbed onto soil and sediment. In addition, PCBs can often be accompanied by other potential contaminants such as plasticizers, chlorinated pesticides, polychlorinated dioxins, and polyaromatic hydrocarbons . In this context, a considerable body of literature exists describing a wide range of methods and techniques for the determination of PCBs in various matrices .…”

mentioning

confidence: 99%

“…In addition, PCBs can often be accompanied by other potential contaminants such as plasticizers, chlorinated pesticides, polychlorinated dioxins, and polyaromatic hydrocarbons. [19,20] In this context, a considerable body of literature exists describing a wide range of methods and techniques for the determination of PCBs in various matrices. [21][22][23] These methods include high-performance liquid chromatography (HPLC), [17] HPLC-GC/MS, [24] gas chromatography-electron capture detector (GC-ECD), [25] electron ionization (EI), [26] GC/MS, etc.…”

mentioning

confidence: 99%

Detection of isocyanates and polychlorinated biphenyls using proton transfer reaction mass spectrometry

Agarwal

Jürschik

Sulzer

et al. 2012

Rapid Comm Mass Spectrometry

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Utilizing recent developments and improvements in PTR-MS, we can rapidly detect two important environmental pollutant compound classes (isocyanates and PCBs) at high accuracy and without any sample preparation. In this paper, we provide proof of the detection of traces of isocyanates and PCBs in air and also of PCBs in liquids. These results could be used for the development of a real-time monitoring device for industrial waste, polluted air or water quality surveillance.

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Statistical method to evaluate clean-up procedures in polychlorinated biphenyl analysis

Cited by 11 publications

References 28 publications

Signal processing to evaluate parameters affecting SPE for multi‐residue analysis of personal care products

Signal processing to evaluate parameters affecting SPE for multi‐residue analysis of personal care products

GC—MS in Space Research: Decoding Complex Isothermal Chromatograms Recovered from Space Missions

Detection of isocyanates and polychlorinated biphenyls using proton transfer reaction mass spectrometry

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