State-of-the-art SPECT/CT: technology, methodology and applications—defining a new role for an undervalued multimodality imaging technique

Beyer, Thomas; Veit-Haibach, Patrick

doi:10.1007/s00259-014-2696-8

Cited by 8 publications

(2 citation statements)

References 15 publications

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“…The CT component of this system utilized a lowdose, non-spiral CT scanner, whose images lacked diagnostic quality but allowed fairly precise localization of SPECT foci of abnormal tracer uptake, CT diagnosis of gross morphological abnormalities, and attenuation correction of the SPECT images as well. Since then, these technologies have considerably advanced, with current SPECT/CT systems offering a wide array of diagnostic quality, multislice spiral CT scanners (for review, see [8]). …”

Section: Introductionmentioning

confidence: 99%

Skeletal SPECT/CT: a review

Kuwert

2014

Clin Transl Imaging

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Skeletal scintigraphy is one of the most frequent in vivo procedures in the field of nuclear medicine. Visualizing bone metabolism, it exhibits a fairly high sensitivity to detect skeletal lesions, but has limitations in terms of specificity and spatial resolution, even when single-photon emission computed tomography (SPECT) is used. Combining SPECT with X-ray computed tomography helps overcome these limitations. This has, in particular, been shown when diagnosing bone involvement in malignant tumors. Emerging evidence indicates the benefit of hybrid imaging for bone scintigraphy during the workup of painful conditions affecting the back and the extremities. Methodological advances holding considerable promise for further improving its value are the quantitation of skeletal tracer uptake in absolute units, as well as multimodal image reconstruction techniques that have recently become available for use in clinical routine.

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Section: Introductionmentioning

confidence: 99%

Skeletal SPECT/CT: a review

Kuwert

2014

Clin Transl Imaging

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“…Anatomical and functional imaging coexisted for decades until, in the 1990s, the use of combined Banato-metabolic^imaging [5] was proposed and subsequently resulted in the introduction of combined SPECT/CT [6], PET/CT [7] and then PET/MR systems [8] in the first decade of the twenty-first century. Although the adoption of these hybrid imaging systems has varied widely over time and across regions, their clinical traction has grown with resulting diagnostic benefit across a variety of clinical applications [9][10][11].…”

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confidence: 99%