State of the art paper Influence of lifestyle on the course of type 1 diabetes mellitus

Piłaciński, Stanisław; Zozulińska-Ziółkiewicz, Dorota A.

doi:10.5114/aoms.2014.40739

Cited by 28 publications

(22 citation statements)

References 93 publications

(94 reference statements)

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“…She adheres to regular follow ups. Evidences of cases of type 1 diabetes due to disturbed lifestyle are increasing [13]. Dietary intervention is a great help to medical science in curbing type 1 diabetes in a higher percentage, without causing any side effects.…”

Section: Discussionmentioning

confidence: 99%

Reversal of type 1 diabetes using plant-based diet: A case study.

Chowdhury¹

2019

biomedicalresearch

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Type-1 diabetes is an autoimmune disease characterized by hyperglycemia, inability to produce insulin due to self-destruction of beta cells in the pancreas. The epidemic of type-1 diabetes causes irreversible suffering like retinopathy, nephropathy, neuropathy, foot complications, high blood pressure, etc, and put patients on a life sentence with insulin. The common perception in medical science is that sugar levels cannot be normalized without the help of medication. However, in the present study we examined a type 1 patient by putting her on a diet plan with regular follow ups and studied all diabetes-related biochemical parameters. We were successfully able to eliminate her medication and insulin dependency.

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Section: Discussionmentioning

confidence: 99%

Reversal of type 1 diabetes using plant-based diet: A case study.

Chowdhury¹

2019

biomedicalresearch

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“…Pilacinski et al suggested a correlation between a lack of physical activity and type I diabetes. The researchers point out that exercise increases insulin sensitivity, which has beneficial effect on the patients [13]. …”

Section: Discussionmentioning

confidence: 99%

Reduction of sitting time has a positive effect on the decrease of insulin resistance in patients with non-alcoholic fatty liver disease

Sabinicz

Maciejewska

Kaczorowska

et al. 2016

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IntroductionNon-alcoholic fatty liver disease (NAFLD) affects a large part of the human population. One of the major environmental factors associated with the risk of NAFLD is the lack of physical activity.AimTo compare the level of physical activity and the insulin resistance in NAFLD patients.Material and methodsThirty patients with NAFLD underwent a six-month dietary intervention based on the principles of classical dietetics. Data about diet and physical activity was based on 72-hour nutrition diaries and International Physical Activity Questionnaire (IPAQ). Standard blood biochemical analyses were carried out before and after diet at the University Hospital Laboratory.ResultsThe study showed that total physical activity and physical activity in leisure time are negatively correlated with insulin resistance (HOMA-IR) (p < 0.05). Insulin (p < 0.05), body weight (p < 0.05), and waist-hip ratio (WHR) (p < 0.05) were also negatively correlated with physical activity in free time. In addition, we noticed a positive correlation between sitting time and the risk of insulin resistance, in the case of HOMA-IR and insulin concentration (p < 0.05).ConclusionsDietary intervention and a physical activity plan are important factors in the treatment of non-alcoholic fatty liver disease. Taking regular exercise increases insulin sensitivity and prevents further development of the disease. It seems that diet and physical activity are not the only one risk factors of NAFLD. Our study reveals that the reduction of sitting time has a positive effect on the level of insulin and it reduces insulin resistance in patients with NAFLD.

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“…Insulin pump therapy is more effective and safer for maintaining glycemic control. It minimizes diabetes-associated complications, provides higher flexibility in daily life, and improves quality of life (13,16,17). Pumps provide an accurate history of insulin use through their menus and often this history can be uploaded and displayed as a graph for purposes of trend analysis.…”

Section: Discussionmentioning

confidence: 99%

An Unusual Trigger for Cutaneous Mastocytosis: The Insulin Pump

Akelma¹,

Buluş²,

Koçak³

et al. 2017

Asthma Allergy Immunol

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ÖZMastositoz cilt başta olmak üzere kemik iliği, karaciğer, dalak, lenf nodları ve gastrointestinal sistemde mast hücrelerinin klonal artışı karakterize nadir görülen bir hastalıktır. Bazı faktörlerin mastositozlu hastaların semptomlarını tetiklediği bilinmektedir. Bu yazıda, Tip 1 diabetes mellitus (DM) olan hastada, insülin pompa tedavisine bağlı semptomları tetiklenen kutanöz mastositoz olgusu sunulmuştur. Kutanöz mastositoz ve Tip 1 DM tanısı konulan 13 yaşındaki erkek çocukta, insülin pompa ile verilen insülin lispro tedavisinden 2-3 gün sonra meydana gelen çok sayıda kaşıntılı papüler lezyonlar görüldü. Mastositoz olarak değerlendirilen lezyonlardan alınan punch biyopside papiller dermiste yaygın mast hücre infiltrasyonu görüldü. Mevcut bulgulardan yola çıkarak, insülin pompa kateterinin lokal mikro travma ile fiziksel uyaran oluşturduğu ve mastositoz lezyonlarının buna bağlı meydana geldiği düşünüldü. Pompa insülin tedavisi kesilip kateter uygulamasından vazgeçildi. İzleminde yeni lezyon çıkmadığı ve gluteal ve periumblikal bölgedeki lezyonların da hiperpigmentasyon ile düzeldiği görüldü. Doğrulama için yeniden insülin pompa kateteri takılan yerlerde 3 gün sonra aynı lezyonlar tekrarladı. Bu olgu nedeniyle, en az 48 saatlik süre boyunca cilt altında kalan kateterin, mastositozda lezyonları tetikleyebileceğini literatürde ilk defa ortaya koyduk. ABSTRACTMastocytosis is a relatively infrequent disorder characterized by mast cell proliferation within primarily the skin, but also various organs such as the bone marrow, liver, spleen, lymph nodes and the gastrointestinal system. Several factors are known to induce symptoms in patients with mastocytosis. A 13-year-old boy with cutaneous mastocytosis and type 1 diabetes mellitus developed multiple itchy papules 2 to 3 days after he started receiving insulin (lispro) pump therapy. Punch biopsy revealed widespread mast cell infiltration on the papillary dermis. We hypothesized that the insulin pump catheter caused a physical stimulus due to local microtrauma and resulted in the formation of the lesions. We, therefore, discontinued insulin pump treatment and switched to SC insulin therapy. While previous lesions healed successfully, no new lesions occurred. To confirm our hypothesis, we repeated the procedure and observed the occurrence of similar lesions around the insulin pump catheter. Herein, we present for the first time, a patient with type 1 diabetes mellitus and cutaneous mastocytosis who developed exacerbation of lesions during insulin pump therapy.Anahtar kelimeler: Mastositoz, kateter, tetikleyici

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State of the art paper Influence of lifestyle on the course of type 1 diabetes mellitus

Cited by 28 publications

References 93 publications

Reversal of type 1 diabetes using plant-based diet: A case study.

Reversal of type 1 diabetes using plant-based diet: A case study.

Reduction of sitting time has a positive effect on the decrease of insulin resistance in patients with non-alcoholic fatty liver disease

An Unusual Trigger for Cutaneous Mastocytosis: The Insulin Pump

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