State‐of‐the‐art molecular imprinted colorimetric sensors and their on‐site inspecting applications

Abstract

Molecular imprinted colorimetric sensors can realize visual semi-quantitative analysis without the use of any equipment. With the advantages of low cost, fast response, ease of handling, and excellent recognition ability, the molecular imprinted colorimetric sensor shows great application potential in the field of sample rapid assay. Molecular imprinted colorimetric sensors can be prepared in various forms to meet the needs of different sample determination, such as film, hydrogel, strip, and adsorption coating. In this review, the preparation methods for various types of molecularly imprinted colorimetric sensors are systematically introduced. Their applications in the field of on-site biological sample detection, drug detection, disease treatment, chiral substance detection and separation, environmental analysis, and food safety detection are introduced. The limitations encountered in the practical application are presented, and the future development directions prospect.

Recent Developments in the Detection of Organic Contaminants Using Molecularly Imprinted Polymers Combined with Various Analytical Techniques

“…Furthermore, the sample's composition must be straightforward, and color rendering should be resistant to interferences. Nevertheless, the unique combination of the colorimetric sensor with MIT can remarkably address this drawback, allowing for the analysis of more complex samples with great potential for practical applications [145]. Since MICSs are widely used to determine various contaminants, some interesting reports are presented as follows, divided into four categories: food safety, environmental analysis, biological sample detection, and drug detection and medical treatment.…”

“…Thus, the detection methods for food safety in daily life must provide good selectivity, low cost, low LODs, high sensitivity, easy portability, handling, and, most importantly, minimal reliance on instrumentation. These values can be achieved via the use of MICSs [145].…”

“…The utilization of MICSs (molecularly imprinted colorimetric sensors) in this industry enables on-site sample analysis, offering rapid results. Additionally, polymer platforms are relatively cost-effective and mitigate significant drawbacks, such as fluctuations, time consumption, and the need for extensive testing personnel and equipment [145].…”

Molecularly Imprinted Polymer-Based Sensors for the Detection of Skeletal- and Cardiac-Muscle-Related Analytes

“…Although the sensor was efficient, the binding analysis when MIP was immersed in 1–100 nM BPA showed that the binding sites in the MIP were not uniform, with one type of binding sites with high affinity and the other types with low affinity. Furthermore, Wang et al wrote an interesting review on the fabrication and the advantages of the combination of colorimetric sensors and MIP sensors to obtain molecularly imprinted colorimetric sensors (MICSs) [ 83 ]. Furthermore, Hamed and Li wrote a review on MIP-based sensors for bisphenol A [ 84 ].…”

A novel bio-template route to synthesize enzyme-immobilized MOF/LDH tubular magnetic micromotors and their application in water treatment

“…2 The colorimetric detection operation is simple and low-cost and has high detection sensitivity, high selectivity and anti-interference ability. 3 Shu et al 4 used TMB (3,3′,5,5′-tetramethylbenzidine) as a colorimetric probe to detect ascorbic acid (AA). In a weakly acidic medium, Ag + oxidized TMB to oxidized TMB (ox-TMB) and produced a solution with a blue absorption peak centered at 652 nm.…”