State-of-the-Art Differentiation Protocols for Patient-Derived Cardiac Pacemaker Cells
Eleonora Torre,
Matteo E. Mangoni,
Alain Lacampagne
et al.
Abstract:Human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes raise the possibility of generating pluripotent stem cells from a wide range of human diseases. In the cardiology field, hiPSCs have been used to address the mechanistic bases of primary arrhythmias and in investigations of drug safety. These studies have been focused primarily on atrial and ventricular pathologies. Consequently, many hiPSC-based cardiac differentiation protocols have been developed to differentiate between atrial- or ventricul… Show more
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