Star-shaped poly(2-methyl-2-oxazoline)-based films: rapid preparation and effects of polymer architecture on antifouling properties

Zhang, Chong; Liu, Songtao; Tan, Lin; Zhu, Haikun; Wang, Yanmei

doi:10.1039/c5tb00732a

Cited by 49 publications

(27 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The degradation of PEG in several oxidative environments, such as in the presence of reactive oxygen species and other biologically relevant conditions that include pH, UV, and cell culture medium, has been studied extensively . Poly(2‐oxazoline)’s derivatives including poly(2‐methyl‐2‐oxazoline) (PMOXA) and poly(2‐ethyl‐2‐oxazoline) (PEOXA) are emerging as alternatives to the widely applied PEG coatings. One of the authors has conducted a few systematic comparative studies between PMOXA‐ and PEG‐based polymer brushes and showed that the higher stability of PMOXA to antifouling properties, in comparison to PEG brushes, is most likely due to the peptidomimetic structure along the PMOXA backbone.…”

Section: Introductionmentioning

confidence: 99%

Investigation of design parameters in generating antifouling and lubricating surfaces using hydrophilic polymer brushes

Pidhatika

Nalam

2019

J of Applied Polymer Sci

View full text Add to dashboard Cite

Long-term stability of hydrophilic surface coatings that prevent fouling, cell adhesion and present a lubricious interface for biomaterials has been widely investigated in recent years. As an alternative to the gold standard poly(ethylene glycol) (PEG), poly(2-oxazoline)based coatings are promising due to their higher stability against oxidative degradation in comparison to PEG. In this study, we compare the antifouling and tribological properties of PEG and poly(2-methyl-2-oxazoline) (PMOXA) brush structures as a function of structural design parameters such as grafting density, chain length, and the monomer solubility. Brush properties such as hydration (number of H 2 O molecules per monomer), shear modulus, and serum adsorption as a function of design parameters were estimated using optical waveguide lightmode spectroscopy and quartz crystal microbalance/dissipation techniques. At high monomer surface densities, PMOXA showed approximately three times higher structurally associated H 2 O molecules per monomer in comparison to PEG brushes, leading to stiffer PMOXA brushes. We found that the chain stiffening of PMOXA brushes lead to higher macroscopic coefficients of friction; however presented similar adsorbed serum mass (high antifouling properties) when compared to PEG brushes.

show abstract

Section: Introductionmentioning

confidence: 99%

Investigation of design parameters in generating antifouling and lubricating surfaces using hydrophilic polymer brushes

Pidhatika

Nalam

2019

J of Applied Polymer Sci

View full text Add to dashboard Cite

show abstract

“…As shown in Figure S5(a) (Supporting Information), the N 1s high‐resolution scan of PDA coating can be curve fitted into two peaks with CN (N, N) and ammonium salt/CNH 3 + . After grafting PMOXA chains to the PDA coating further, an additional peak NCO (~400.17 eV) appeared [Figure S5(b), Supporting Information], meaning that PMOXA was grafted to PDA‐modified surface successfully . While grafting PAA‐SH to the PDA/PMOXA‐coated surface further, an obvious peak (S 2p) at 166.4 eV appears as shown in Figure S4 (Supporting Information); meanwhile, the peak area of NCO decreased when PAA being grafted to the PDA/PMOXA‐coated surface which means PAA chains were grafted successfully [Figure S5(c), Supporting Information].…”

Section: Resultsmentioning

confidence: 99%

“…In order to get a detailed view of the film surface composition ulteriorly, the XPS high‐resolution C 1s scans of mixed brushes were also studied (Figure S6, Supporting Information). The C 1s core‐level spectra are curve fitted into five peak components with binding energy at about 284.79, 285.2, 285.95, 287.99, and 288.8 eV attributable to CC/CH, CCOOH, CN/CO, CO, and COOH, respectively . The XPS‐derived percentage content of COOH (Table ) increased with increasing the concentration of PAA‐SH solution used for the preparation of mixed brushes coating.…”

Section: Resultsmentioning

confidence: 99%

Influence of poly(acrylic acid) grafting density on switchable protein adsorption/desorption of poly(2‐methyl‐2‐oxazoline)/poly(acrylic acid) mixed brushes

Gong

Pan

et al. 2019

J of Applied Polymer Sci

Self Cite

View full text Add to dashboard Cite

Poly(dopamine) is employed as an anchor to obtain a series of poly(acrylic acid) (PAA) and poly(2-methyl-2-oxazoline) (PMOXA) mixed brush coatings by sequential grafting to methods with PAA chains longer than PMOXA chains. Then, the prepared mixed brush coatings are rigorously characterized. The results show that the grafting density of PAA in mixed brushes could be well adjusted by changing the concentration of PAA solution used for the preparation of mixed brush coatings and the amounts of lysozyme adsorbed on PMOXA/PAA mixed brushes increase with increasing the grafting density of PAA chains while the desorption amounts decrease significantly when the grafting density of PAA is higher than one-half of PMOXA chains. When the grafting density of PAA is about one-half of PMOXA chains, the mixed brush could absorb high amounts of lysozyme (898.4 ng cm −2 ), and then more than 90% of adsorbed proteins could be released sharply by changing pH and ionic strength (I).

show abstract

“…Entrapment : Polycatecholamine coating can also be physically modified by incorporation of other materials while undergoing polymerization. This can entrap materials within the coating that may not contain the reactive groups necessary for covalent attachment (e.g., polyethylene glycol, polyvinylalcohol, hyaluronic acid, polyacrylamide, heparin, polyzwitterions, poly( N ‐isopropylacrylamide), other hydrophilic functional materials, and antibacterial compounds). Polydopamine and norepinephrine‐based coatings have also been used to physically entrap both small molecules and proteins during formation.…”

Section: Catecholamine Polymers: Chemistry and Structurementioning

confidence: 99%

“…Following this approach, polydopamine and other catecholamines have been modified with various fouling resistant materials and antimicrobial compounds to prevent biofouling of the surfaces . These include hydrophilic antifouling polymers, zwitterionic amino acids, bioinspired antimicrobial compounds, lysing and disinfecting agents, silver nanoparticles, combinations of silver nanoparticles and antifouling polymers, bactericidal enzymes, and the attachment of multidrug eluting polyelectrolyte multilayer coatings …”

Section: Applications Of Catecholamine Polymersmentioning

confidence: 99%

Versatile Surface Modification Using Polydopamine and Related Polycatecholamines: Chemistry, Structure, and Applications

Barclay

Hegab

Clarke

et al. 2017

Adv Materials Inter

292

223

View full text Add to dashboard Cite

Almost ten years ago, Lee et al. [13] formulated a universal adhesive coating based on observation of the strong attachment by mussels through their byssal threads to virtually all types of inorganic and organic surfaces. The amino acid compositions of the mussel foot proteins that generate the attachment are rich in catechol and amine groups. [13][14][15] These groups associate under marine conditions, forming strong covalent and noncovalent interactions with substrates. [13] This led to the idea that both catechol and amine groups were crucial in forming robust, wide spectrum adhesive nanolayers [16,17] and consequently dopamine was conceived as a powerful building block for spontaneous deposition of thin polymer films. The dopamine monomer is deposited onto unadulterated surfaces through self-assembly and oxidative cross-linking from mild pH aqueous solution in a rapid reaction. This results in a durable, nanoscale, conformal, and hydrophilic coating that can be readily modified to introduce specific surface chemistries for a particular application. [18][19][20][21][22] These bioinspired, polydopamine materials are chemically and structurally indistinguishable from eumelanins found in the human body, [23,24] providing excellent biocompatibility. Additionally, polydopamine has broad electromagnetic absorption and excellent photothermal energy conversion [25] as well as having ionic-electronic hybrid conductivity. [26] Along with the excellent coating performance, these properties provide a vast array of potential applications for polydopamine materials.In this article, we explain what is known about polydopamine and related catecholamine coatings; their formation, the adhesion mechanism, and their physicochemical properties and we also review the applications of these materials (Figure 1). Since 2011, there have been a number of reviews on this subject matter, including general reviews on the physicochemical properties of polydopamine coatings [11,20,[27][28][29] and their applications. [20,27,30] There are also a number of more specific reviews on the chemical synthesis and modulation of polycatecholamine coatings, [31] the biomedical applications of these coatings, [8,[32][33][34] their electronic properties, [26,35] the use of polydopamine to make films at fluid interfaces, [36] in hierarchically constructed particles, [33] and capsules, [30] exploitation of polycatecholamine coatings in membrane filtration, [37] polydopamine-derived carbon materials, [38] and the use of coordination chemistry in catechol-based materials. [39] Nonetheless, this area of research is growing so rapidly [25,27] that many recent Polydopamine and related polycatecholamines can be easily deposited onto almost any surface from mild, aqueous solution. This results in durable, nanoscale coatings that exhibit high biocompatibility and have useful chemical and electronic properties. Additionally, these materials can be readily chemically and physically modified, and consequently, they are used extensively for surface modification. This ...

show abstract

Star-shaped poly(2-methyl-2-oxazoline)-based films: rapid preparation and effects of polymer architecture on antifouling properties

Abstract: Star-shaped poly(2-methyl-2-oxazoline)-based films prepared through polydopamine-assistance provided enhanced antifouling properties than the linear ones, and showed superior stability than PEG films.

Cited by 49 publications

References 61 publications

Investigation of design parameters in generating antifouling and lubricating surfaces using hydrophilic polymer brushes

Investigation of design parameters in generating antifouling and lubricating surfaces using hydrophilic polymer brushes

Influence of poly(acrylic acid) grafting density on switchable protein adsorption/desorption of poly(2‐methyl‐2‐oxazoline)/poly(acrylic acid) mixed brushes

Versatile Surface Modification Using Polydopamine and Related Polycatecholamines: Chemistry, Structure, and Applications

Contact Info

Product

Resources

About