Staphylococcus warneri: Skin Commensal and a Rare Cause of Urinary Tract Infection

Kanuparthy, Aparna; Challa, Tejo; Meegada, Sreenath; Siddamreddy, Suman; Muppidi, Vijayadershan

doi:10.7759/cureus.8337

Cited by 14 publications

(12 citation statements)

References 11 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the same time, the proportion of such bacteria as Staphylococcus saprophyticus , Staphylococcus epidermidis , and Staphylococcus warneri correlated with passenger traffic. Other representatives of the cultivated microbiome were widespread microorganisms, which are rarely evaluated as pathogens [ 30 , 33 , 34 , 35 , 36 , 37 , 38 ].…”

Section: Discussionmentioning

confidence: 99%

Microbiological Characteristics of Some Stations of Moscow Subway

Pochtovyi

Vasina

Verdiev

et al. 2022

Biology

View full text Add to dashboard Cite

The subway is one of the most actively used means of transport in the traffic infrastructure of large metropolitan areas. More than seven million passengers use the Moscow subway every day, which promotes the exchange of microorganisms between people and the surrounding subway environment. In this research, a study of the bacterial communities of two Moscow subway stations was conducted and the common subway microbiome was determined. However, there were differences in microbiological and antibiotic-resistance profiles, depending on the station. The station’s operational period since opening correlated with the taxonomic diversity and resistance of the identified bacteria. Moreover, differences between aerosol and surface bacterial communities were found at the two subway stations, indicating the importance of diversified sampling during the microbiome profiling of public areas. In this study, we also compared our data with previously published results obtained for the Moscow subway. Despite sample collection at different stations and seasons, we showed the presence of 15 common genera forming the core microbiome of the Moscow subway, which represents human commensal species, as well as widespread microorganisms from the surrounding environment.

show abstract

Section: Discussionmentioning

confidence: 99%

Microbiological Characteristics of Some Stations of Moscow Subway

Pochtovyi

Vasina

Verdiev

et al. 2022

Biology

View full text Add to dashboard Cite

show abstract

“…Of the Py4-sensitive Staphylococcus, S. warneri is a commensal skin bacterium that is an opportunistic pathogen that can cause serious diseases in humans such as native valve endocarditis, ventriculoatrial shunt and ventriculoperitoneal shunt infections, meningitis, botryomycosis, urinary tract infection, multifocal discitis, septic arthritis, and vertebral osteomyelitis [53][54][55][56][57][58][59][60][61][62][63][64][65]. Therefore, in addition to the potential value of Py4 against the clinical isolates of Staphylococcus, its potent activity on S. warneri by targeting the cell-wall biosynthesis should be further explored.…”

Section: Discussionmentioning

confidence: 99%

A Fungal Defensin Inhibiting Bacterial Cell-Wall Biosynthesis with Non-Hemolysis and Serum Stability

Gao

Zhu

2022

JoF

View full text Add to dashboard Cite

Defensins are a class of cationic disulfide-bridged antimicrobial peptides (AMPs) present in many eukaryotic organisms and even in bacteria. They primarily include two distinct but evolutionarily related superfamilies (cis and trans). Defensins in fungi belong to the members of the cis-superfamily with the cysteine-stabilized α-helical and β-sheet fold. To date, many fungal defensin-like peptides (fDLPs) have been found through gene mining of the genome resource, but only a few have been experimentally characterized. Here, we report the structural and functional characterization of Pyronesin4 (abbreviated as Py4), a fDLP previously identified by genomic sequencing of the basal filamentous ascomycete Pyronema confluens. Chemically, synthetic Py4 adopts a native-like structure and exhibits activity on an array of Gram-positive bacteria including some clinical isolates of Staphylococcus and Staphylococcus warneri, a conditioned pathogen inhabiting in human skin. Py4 markedly altered the bacterial morphology and caused cytoplasmic accumulation of the cell-wall synthesis precursor through binding to the membrane-bound Lipid II, indicating that it works as an inhibitor of cell-wall biosynthesis. Py4 showed no hemolysis and high mammalian serum stability. This work identified a new fungal defensin with properties relevant to drug exploration. Intramolecular epistasis between mutational sites of fDLPs is also discussed.

show abstract

“…These groups of bacteria, some of which are fish pathogens, are commonly found in aquatic environments [ 12 , 25 , 34 , 35 , 37 , 38 ]. All these bacteria were already associated with human infections, such as ear and eye infections, osteomyelitis, infective arthritis, endocarditis, bacteremia, meningitis, intestinal and urinary tract infections, brain abscess, peritonitis, enteritis and septicemia, and some are recognized as important agents in nosocomial infections [ 12 , 13 , 34 , 37 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ].…”

Section: Discussionmentioning

confidence: 99%

Assessing the Bacterial Community Composition of Bivalve Mollusks Collected in Aquaculture Farms and Respective Susceptibility to Antibiotics

et al. 2021

View full text Add to dashboard Cite

Aquaculture is a growing sector, providing several products for human consumption, and it is therefore important to guarantee its quality and safety. This study aimed to contribute to the knowledge of bacterial composition of Crassostrea gigas, Mytilus spp. and Ruditapes decussatus, and the antibiotic resistances/resistance genes present in aquaculture environments. Two hundred and twenty-two bacterial strains were recovered from all bivalve mollusks samples belonging to the Aeromonadaceae, Bacillaceae, Comamonadaceae, Enterobacteriaceae, Enterococcaceae, Micrococcaceae, Moraxellaceae, Morganellaceae, Pseudomonadaceae, Shewanellaceae, Staphylococcaceae, Streptococcaceae, Vibrionaceae, and Yersiniaceae families. Decreased susceptibility to oxytetracycline prevails in all bivalve species, aquaculture farms and seasons. Decreased susceptibilities to amoxicillin, amoxicillin/clavulanic acid, cefotaxime, cefoxitin, ceftazidime, chloramphenicol, florfenicol, colistin, ciprofloxacin, flumequine, nalidixic acid and trimethoprim/sulfamethoxazole were also found. This study detected six qnrA genes among Shewanella algae, ten qnrB genes among Citrobacter spp. and Escherichia coli, three oqxAB genes from Raoultella ornithinolytica and blaTEM-1 in eight E. coli strains harboring a qnrB19 gene. Our results suggest that the bacteria and antibiotic resistances/resistance genes present in bivalve mollusks depend on several factors, such as host species and respective life stage, bacterial family, farm’s location and season, and that is important to study each aquaculture farm individually to implement the most suitable measures to prevent outbreaks.

show abstract

Staphylococcus warneri: Skin Commensal and a Rare Cause of Urinary Tract Infection

Cited by 14 publications

References 11 publications

Microbiological Characteristics of Some Stations of Moscow Subway

Microbiological Characteristics of Some Stations of Moscow Subway

A Fungal Defensin Inhibiting Bacterial Cell-Wall Biosynthesis with Non-Hemolysis and Serum Stability

Assessing the Bacterial Community Composition of Bivalve Mollusks Collected in Aquaculture Farms and Respective Susceptibility to Antibiotics

Contact Info

Product

Resources

About