Staphylococcus simulans: A rare uropathogen

Abstract

Urinary tract infections (UTIs) are clinically and economically burdensome. Gram positive causative uropathogens are rare, and Staphylococcus simulans has infrequently been isolated as a causative agent for UTIs. Here, we present two cases of S. simulans causing complicated urinary tract infections.

BACTERIOLOGICAL STUDY OF COAGULASE-NEGATIVE Staphylococcus spp ISOLATED FROM URINARY TRACT INFECTION AND THEIR RESISTANCE TO ANTIBIOTICS

“…S. hominis and S.lugdunensis bacteria were both highly sensitive to the antibiotics Rifampcin, Amikacin, Methicillin and Levofloxacin and moderately sensitive to Vanomycin .These results match those of the researcher (Onyebueke et al, 2019), who found that S. hominis bacteria were resistant to antibiotics containing Amoxicillin / Clavulanic Acid and had different levels of sensitivity to other antibiotics. For S..lugdunensi bacteria, our results were the same as the researcher's (Luty et al, 2020), where the bacteria was highly sensitive to the Levofloxacin and resistant to the rest of the antibiotics while with the S.simulans the result was agreed with the researcher (Drobeniuc et al,2021). Even though these bacteria are rare, they can cause endocarditis, bacteremia, and urinary tract infections.…”

Petting Zoos as an Unsuspected Source of Pediatric Infections

“…While both organisms have previously been implicated in human infection, reports of pediatric infection are rare. [9][10][11][12][13][14][15][16] In addition, these bacteria are strongly associated with animal infections, especially in cattle. The rarity of human infection from these organisms and the match between their ecologic niches and these children's preinfection exposures suggests that these infections may have been acquired during petting zoo visits.…”

Acute Focal Bacterial Nephritis Caused by Staphylococcus simulans

“…To the best of our knowledge, this is the first report of AFBN caused by S. simulans in children. S. simulans, coagulase-negative staphylococci, is a common farm animal pathogen that occasionally colonizes human skin [3]. S. simulans has been reported to cause soft tissue infections, endocarditis, bacteremia, osteomyelitis, prosthetic joint infections, and urinary tract infections [3].…”

“…S. simulans, coagulase-negative staphylococci, is a common farm animal pathogen that occasionally colonizes human skin [3]. S. simulans has been reported to cause soft tissue infections, endocarditis, bacteremia, osteomyelitis, prosthetic joint infections, and urinary tract infections [3]. Patients with S. simulans infections had often been in close contact with farm animals in previous reports [3,4]; however, several pediatric cases of S. simulans infection without exposure to farm animals have been reported [4,5].…”

“…S. simulans has been reported to cause soft tissue infections, endocarditis, bacteremia, osteomyelitis, prosthetic joint infections, and urinary tract infections [3]. Patients with S. simulans infections had often been in close contact with farm animals in previous reports [3,4]; however, several pediatric cases of S. simulans infection without exposure to farm animals have been reported [4,5]. Although our patient did not have a definite contact history with a domesticated animal, she sometimes did have contact with a neighbor's dog.…”