Staphylococcus saprophyticus found to be a common contaminant of food

Hedman, Per; Ringertz, Olof; Eriksson, Beatrice; Kvarnfors, P.; Andersson, Mats; Bengtsson, Lena; Olsson, Kerstin

doi:10.1016/0163-4453(90)90554-l

Cited by 43 publications

(24 citation statements)

References 16 publications

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“…The infectious source of S. saprophyticus causing UTI in women is unknown. However, it has been shown that S. saprophyticus is widely spread in the ecosystem and that a variety of food products are contaminated, leading to the colonization of the human gastrointestinal tract (8). Furthermore, rectal, vaginal, or urethral colonization with S. saprophyticus has been associated with UTI (17).…”

Section: Discussionmentioning

confidence: 99%

Molecular Epidemiology of Staphylococcus saprophyticus Isolated from Women with Uncomplicated Community-Acquired Urinary Tract Infection

et al. 2007

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Staphylococcus saprophyticus is a common cause of urinary tract infections (UTIs) in women. Little is known about the molecular epidemiology of S. saprophyticus UTIs. In the current study, we compared 76 isolates of S. saprophyticus prospectively isolated from women with uncomplicated UTI participating in a randomized placebo-controlled treatment trial performed in northern Sweden from 1995 to 1997 with 50 strains obtained in 2006 from five different locations in northern Europe with pulsed-field gel electrophoresis (PFGE). The aim was to elucidate the molecular epidemiology of this uropathogenic species and to investigate whether specific clones are associated with UTI in women. A total of 47 different PFGE profiles were detected among the 126 analyzed isolates. Ten clusters consisting of 5 to 12 isolates each showing PFGE DNA similarity of >85% were identified. Several clusters of genetically highly related isolates were detected in the original trial as well as among isolates obtained during 2006 from different locations. In the original trial, clonal persistence was found among 16 of 21 (76%) patients examined in the placebo group at follow-up 8 to 10 days after inclusion, indicating a low spontaneous short-time bacteriological cure rate. We conclude that multiple clones of S. saprophyticus were causing lower UTIs in women. The result suggests that some human-pathogenic clones of S. saprophyticus are spread over large geographical distances and that such clones may persist over long periods of time.

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Section: Discussionmentioning

confidence: 99%

Molecular Epidemiology of Staphylococcus saprophyticus Isolated from Women with Uncomplicated Community-Acquired Urinary Tract Infection

et al. 2007

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“…The seasonal variation in the prevalence of colonization by S. saprophyticus in cattle and pigs was similar to that of UTIs in humans. The microorganism was found to contaminate 16.4% of various food samples in Sweden, with a high prevalence of 34% in samples of raw beef and pork [24][25]. Nevertheless, S. saprophyticus UTI can occur in women who are vegetarians [6].…”

Section: B R I E F R E P O R Tmentioning

confidence: 97%

Who Are You--Staphylococcus saprophyticus?

Raz

Colodner

Kunin

2005

Clinical Infectious Diseases

154

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“…As a consequence, resistance to these antibiotics has been poorly documented in S. saprophyticus in comparison with other CoNS. Although S. saprophyticus appears to be an exclusive uropathogen, its major reservoir is the gastrointestinal tract, with the most common site being the rectum [7], and its mode of transmission may be through consumption of contaminated animal food products [8]. A study in the UK [9] as well as preliminary results from University Hospital of Caen (France) (unpublished data) showed a high prevalence of MLS resistance in S. saprophyticus, indicating that this species might be a potential reservoir of MLS resistance genes.…”

Section: Introductionmentioning

confidence: 99%

Molecular basis of resistance to macrolides, lincosamides and streptogramins in Staphylococcus saprophyticus clinical isolates

Bouter

Leclercq

Cattoir

2011

International Journal of Antimicrobial Agents

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The aim of this study was to evaluate the prevalence of resistance to macrolide-lincosamide-streptogramin (MLS) antibiotics as well as to assess the molecular basis of this resistance amongst 72 Staphylococcus saprophyticus urinary isolates collected from 2005 to 2009 in University Hospital of Caen (France). Of the 72 strains studied, 33 (45.8%) were resistant to at least one MLS antibiotic, including 24 (72.7%) with an M phenotype, 5 (15.2%) with an inducible MLS(B) phenotype, 3 (9.1%) with a combined M+L phenotype and 1 (3.0%) with an L phenotype. All isolates were susceptible to the combination of streptogramins A and B. The resistance genes erm(A), erm(B), erm(C), msr(A) and lnu(A) were detected alone in 0, 0, 5 (15.2%), 24 (72.7%) and 1 (3.0%) of the 33 MLS-resistant isolates, respectively, whereas 2 strains (6.1%) were positive for both msr(A) and lnu(A). All msr(A)-positive isolates exhibited an M phenotype, whereas all five erm(C)-positive and all three lnu(A)-positive strains displayed, respectively, an inducible MLS(B) phenotype and an L phenotype with a positive Hodge test. Plasmid analysis indicated that erm(C) and lnu(A) genes were borne by small-size plasmids (ca. 2.5 kb), whereas larger plasmids (30-90 kb) harboured msr(A). In conclusion, these findings show a high prevalence of MLS resistance in S. saprophyticus, which was mainly associated with the presence of the msr(A) gene. Since S. saprophyticus colonises the gastrointestinal tract, it may constitute an unexpected reservoir for MLS resistance genes, in particular msr(A), amongst coagulase-negative staphylococci.

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Staphylococcus saprophyticus found to be a common contaminant of food

Cited by 43 publications

References 16 publications

Molecular Epidemiology of Staphylococcus saprophyticus Isolated from Women with Uncomplicated Community-Acquired Urinary Tract Infection

Molecular Epidemiology of Staphylococcus saprophyticus Isolated from Women with Uncomplicated Community-Acquired Urinary Tract Infection

Who Are You--Staphylococcus saprophyticus?

Molecular basis of resistance to macrolides, lincosamides and streptogramins in Staphylococcus saprophyticus clinical isolates

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