Staphylococcus pseudoxylosus sp. nov., isolated from bovine mastitis

Macfadyen, Alison; Léroy, Sabine; Harrison, Ewan M.; Parkhill, Julian; Holmes, Mark A.; Paterson, Gavin K.

doi:10.1099/ijsem.0.003416

Cited by 23 publications

(14 citation statements)

References 23 publications

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“…[98] (ZSCHÖCK et al, 2000;Kerro Dego et al, 2002). According Gentilini et al (2002) currently CN Staphylococcus have received greater importance as causative agents of intramammary infections in dairy cattle worldwide (KROL et al, 2016;RASPANTI et al, 2016;HOEKSTRA et al, 2018;MAHMMOD et al, 2018;RONCO et al, 2018;MACFADYEN et al, 2019). The S. aureus is known worldwide as a causative agent of various purulent diseases in both humans and animals (BEAN; GRIFFIN, 1990) is also one of the most important causes of food poisoning (PENNA et al, 1998) due to production of various enterotoxins (OMOE et al, 2002).…”

Section: Results E Discussionmentioning

confidence: 99%

Bacteria From Bovine Mastitis: Survey and Literature Review

dos¹,

Leal²,

Lima³

et al. 2020

Ciência, Tecnologia E Inovação: Do Campo À Mesa

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Section: Results E Discussionmentioning

confidence: 99%

Bacteria From Bovine Mastitis: Survey and Literature Review

dos¹,

Leal²,

Lima³

et al. 2020

Ciência, Tecnologia E Inovação: Do Campo À Mesa

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“…It causes clinical and subclinical intramammary infection with serious economic loss and herd management problems in dairy cows (ZSCHÖCK et al, 2000;Kerro Dego et al, 2002). According Gentilini et al (2002) currently CN Staphylococcus have received greater importance as causative agents of intramammary infections in dairy cattle worldwide (KROL et al, 2016;RASPANTI et al, 2016;HOEKSTRA et al, 2018;MAHMMOD et al, 2018;RONCO et al, 2018;MACFADYEN et al, 2019). The S. aureus is known worldwide as a causative agent of various purulent diseases in both humans and animals (BEAN; GRIFFIN, 1990) is also one of the most important causes of food poisoning (PENNA et al, 1998) due to production of various enterotoxins (OMOE et al, 2002).…”

Section: Results E Discussionmentioning

confidence: 99%

Bacteria From Bovine Mastitis: Survey and Literature Review

Dors¹,

Santos²,

Ladeira³

et al. 2020

Ciência, Tecnologia E Inovação: Do Campo À Mesa

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Subclinical bovine mastitis is the most prevalent and responsible for the loss of 70% in production, reducing milk secretion by 45%. Clinical mastitis shows clinical signs, in addition to reducing production. The objective of this work was to study bovine mastitis in the literature and conduct research on bacteria in cases of mastitis in four dairy farms in the region of Pelotas -RS -Brazil. In addition to bibliographic research, pathogenic aerobic bacteria were isolated and identified in 94 milk samples with clinical mastitis (n = 12) or subclinical (n = 82) with positive CMT (+ + +). The samples collected and previously identified in test tubes were cultured in blood agar and oven 36°C/24 h, and reading the results performed within 24h to 36°C aerobically. Bacterial growth was observed in 62 (65.9%) samples: 12 (19.4%) clinical mastitis and in 50 (80.6%) subclinical mastitis. After identified biochemical characterization: Coagulase negative Staphylococcus sp. (n = 29), Staphylococcus sp. Coagulase positive (n = 6), Corynebacterium spp. (n = 16), Streptococcus spp. (n = 7), Streptococcus uberis (n = 4). The knowledge and identification of the etiological agent is important for the correct treatment and implementation of mastitis control and prevention methods and for herd monitoring.

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“…During the past few years, an increasing number of human infections have been associated with this species such as urinary tract, pancreatic, cardiac, ophthalmologic, dental, blood stream, erythema chest infections, nodosum as well as otogenic brain abscess, to mention a few [9][10][11][12]. Currently, S.xylosus has become the prevalent cause of mastitis in dairy herds in many countries including America, Finland, Canada, Sweden, Switzerland, Norway, and China [13][14][15][16] (Fig. 1).…”

Section: Introductionmentioning

confidence: 99%

“…1). The average proportion of mastitis due to S.xylosus increased year by year according to a nationwide survey [14,17]. S.xylosus can also lead to other diseases in animals including dermatitis in gerbils and immune de cient mice, pulmonary and lymph node lesions in immune de cient mice, or transmural necrotizing cystitis and secondary peritonitis in a 4-month-old male Holstein calf [7,18].…”

Section: Introductionmentioning

confidence: 99%

Molecular Mechanism of Staphylococcus Xylosus Resistance Against Tylosin and Florfenicol

Liu

Shu

Cui

et al. 2021

Preprint

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As a result of evolution, certain microbes develop resistance against antimicrobial treatment. The antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of severe infections caused by microbes such as bacteria, viruses, fungi and other parasites. The resistance of Staphylococcus xylosus (S. xylosus) against antibiotic treatment is one of the major causes of the world-wide antibiotic crisis and has remained to be well understood at the molecular level. In order to fill this gap, we investigated various mutations in the sequence of ribosomal proteins involved cross resistance. We discovered that for the mutant containing the insertion L22 97KRTSAIN98 the minimum inhibitory concentration against both tylosin and florfenicol changed dramatically. To understand this effect on a molecular basis and to further elucidate the role of cross resistance, we computationally constructed the 3D model of the large ribosomal subunit from S. xylosus as well as its complexes with both tylosin and florfenicol. Using all-atom molecular dynamics simulations, we found that unique structural changes in the β hairpin of L22 played a central role of this variant in the development of antibiotic resistance in S. xylosus. In addition, the regulation of protein network also played an essential role in the development of cross resistance in S. xylosus. Our work provides insightful views into the mechanism of S. xylosus resistance which could be useful for the development of the next generation of antibiotics.

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Staphylococcus pseudoxylosus sp. nov., isolated from bovine mastitis

Cited by 23 publications

References 23 publications

Bacteria From Bovine Mastitis: Survey and Literature Review

Bacteria From Bovine Mastitis: Survey and Literature Review

Bacteria From Bovine Mastitis: Survey and Literature Review

Molecular Mechanism of Staphylococcus Xylosus Resistance Against Tylosin and Florfenicol

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