Staphylococcus aureus: resistance pattern and risk factors

Naghavi-Behzad, Mohammad; Akhi, Mohammad Taghi; Alizadeh, Mohammad; Saleh, Parviz; Jafarzadeh, Sajed; Sohrab-Navi, Zahra; Bagheri-Asl, Mohammad Mahdi; Barband, Sharareh; Sadeghi, Ghader; Asghari, Babak; Piri, Reza

doi:10.15171/jarcm.2015.007

Cited by 3 publications

(1 citation statement)

References 28 publications

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“…Nasal or mucocutaneous colonization with MRSA is identified as a potential reservoir for infection in the individual patient as well as transmission to other patients and healthcare workers in several studies (Jafarzadeh et al, 2014). However, other findings suggest that nasal carriage may not be the main acquisition pathway for surgical site infection (SSIs).…”

Section: Section 3: Analytical Epidemiologymentioning

confidence: 99%

Hospital acquired Methicillin Resistant Staphylococcus aureus (MRSA) in Angelina County, Texas

Adelodun¹,

Bako²,

Ejoh³

et al. 2019

Preprint

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Healthcare-associated infections (HAIs) are infections patients are prone to while receiving medical treatment in a healthcare facility and can be defined as ‘healthcare-associated’ if they develop 48 hours after admission, receiving medical care or within 30 days of having a surgical procedure. HAIs occur in all settings of care and across the continuum of care, including hospital acute care units, day procedure centers, ambulatory outpatient clinics, dialysis centers, long-term care facilities, nursing homes, and rehabilitation centers. Risk factors for HAIs include host factors such as compromised immune system due to underlying disease or disruption of mucosal and skin surfaces that increases their risk of developing infections or acquiring organisms that are either high or low virulence. The hospital environment also facilitates the spread of microbial pathogens due to patient proximity, contamination of common equipment, and exposure to water contaminated with microorganisms. Interestingly, new healthcare technologies and methods of monitoring and caring for patients create new portals of entry for infection alter normal host flora, thereby increasing the risk of HAIs.In the United States, the Centers for Disease Control and Prevention (CDC) estimates that nearly 2 million patients experience an HAI each year. This means that 1 in every 10-20 hospitalized patients in the country develops such an infection. These infections cause almost 100,000 deaths and are responsible for an extra $4.5 billion to $6.5 billion in healthcare expenses. We created a plan for solving the problem of HAIs in a Texas county.

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Section: Section 3: Analytical Epidemiologymentioning

confidence: 99%

Hospital acquired Methicillin Resistant Staphylococcus aureus (MRSA) in Angelina County, Texas

Adelodun¹,

Bako²,

Ejoh³

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

Cloning, expression and purification of autolysin from methicillin-resistant Staphylococcus aureus: potency and challenge study in Balb/c mice

Haghighat

Siadat

Sorkhabadi

et al. 2017

Molecular Immunology

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Reports of Vancomycin-Resistant Staphylococcus aureus from Middle East Countries

Rahimipour

Ghazvini

Youssefi

2018

Arch Clin Infect Dis

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Context: Staphylococcus aureus is one of the most important pathogens worldwide. The emergence of methicillin-resistant Staphylococcusaureus (MRSA) made vancomycin as the only therapeutic choice. Due to excessive use of vancomycin, decreased susceptibility and increased resistance against this antibiotic are reported worldwide. The current study aimed at investigating the emergence of vancomycin-resistant Staphylococcus aureus (VRSA) in different regions of the Middle-East. Evidence Acquisition: All reputable databases, such as Google Scholar and PubMed, were screened for articles and abstracts reporting VRSA in the Middle-East by the appropriate keywords. Reliable phenotypic and genotypic studies were included in the current review. Results: Reviewing all articles/abstracts revealed more than 100 reports of VRSA isolates from the Middle-East. Most of the studies did not use the clinical and laboratory standards institute (CLSI) guidelines on VRSA identification. Until 2012, four VRSA strains were reported from Iran, 7 from Egypt, and 1 from Pakistan. From 2012 to 2016, seven VRSA isolates were added to the global statistics from the Middle-East; 1 from Iran and 6 from Egypt. Conclusions: VRSA is a global health threat. According to the expanding reports on the emersion of VRSA, more attention should be paid to the proper prescription of this antibiotic as the only choice for S. aureus infections.

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Staphylococcus aureus: resistance pattern and risk factors

Cited by 3 publications

References 28 publications

Hospital acquired Methicillin Resistant Staphylococcus aureus (MRSA) in Angelina County, Texas

Hospital acquired Methicillin Resistant Staphylococcus aureus (MRSA) in Angelina County, Texas

Cloning, expression and purification of autolysin from methicillin-resistant Staphylococcus aureus: potency and challenge study in Balb/c mice

Reports of Vancomycin-Resistant Staphylococcus aureus from Middle East Countries

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