Staphylococcus aureus Isolated From Normal and Infected Eyes

Locatcher-Khorazo, D.; Sullivan, Nabi; Gutierrez, Elizabeth

doi:10.1001/archopht.1967.00980020372015

Cited by 11 publications

(1 citation statement)

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“…This contrasts with the substantial degree of clonality observed in the present study for S. aureus endophthalmitis isolates. In both S. aureus and S. epidermidis endophthalmitis, a likely source for the infecting organism is the periocular skin, eyelid margins, or nares (22,31). With PFGE used to identify clonal relationships between strains, it was recently shown that nasal colonization patterns by S. aureus and S. epidermidis differ (10,11).…”

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Molecular Epidemiology of Staphylococcus aureus and Enterococcus faecalis in Endophthalmitis

et al. 1998

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Genomic DNA fingerprint analysis was performed on 39Staphylococcus aureus and 28 Enterococcus faecalis endophthalmitis isolates collected from multiple clinical centers. Among 21 S. aureus genomic DNA fingerprint patterns identified, five clonotypes were recovered from multiple unrelated patients and accounted for 58.9% (23 of 39) of the isolates analyzed. Compared with strains having unique genomic DNA fingerprint patterns, the S. aureus clonotypes occurring more than once were more likely to result in visual acuities of 20/200 or worse (P = 0.036 [χ2 test]). In contrast to the S. aureus isolates, the E. faecalis endophthalmitis isolates were a clonally diverse population, enriched for the expression of a known toxin, cytolysin, which is plasmid encoded.

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confidence: 99%