Staphylococcus aureus bacteraemia among patients undergoing dialysis--focus on dialysis catheter-related cases

Abstract

Patients on dialysis are at a high risk of S. aureus bacteraemia and they have a four times higher mortality from central venous catheter-related S. aureus bacteraemia than other patients. There is need for prospective studies in which patients as well as catheters are followed more thoroughly to study the pathogenesis of dialysis catheter-related infections.

Central Venous Catheter-Related Bacteremia in Chronic Hemodialysis Patients: Saudi Single Center Experience

“…In hemodialysis patients with CRB S.aureus is an independent risk factor for both infectious complications and failure of bacteremia treatment (10) .A singlecenter, retrospective study found that, compared with patients not on dialysis, those on dialysis (379 hemodialysis and 31 peritoneal dialysis patients) were four times more likely to die from S. aureus CRB staphylococcus induced (5.3% vs. 1.3%; P<0.001). (11).…”

Central Venous Catheter-Related Bacteremia in Chronic Hemodialysis Patients:Saudi Single Center Experience

“…In hemodialysis patients with CRB S.aureus is an independent risk factor for both infectious complications and failure of bacteremia treatment (10) .A singlecenter, retrospective study found that, compared with patients not on dialysis, those on dialysis (379 hemodialysis and 31 peritoneal dialysis patients) were four times more likely to die from S. aureus CRB staphylococcus induced (5.3% vs. 1.3%; P<0.001). (11).…”

Excellent Prognosis of Culture Negative Endocarditis in Hemodialysis Patients: A Case Series

“…[9,14,16,17] Third, according to microbiology patterns observed in our own institution, 62% of all S. aureus isolated are methicillin-resistant, and these patients require a thrice-weekly dialysis in a hospital facility; thus, the occurrence of MRSA bacteremia may represent a true nosocomial infection carrying a devastating virulence in an immune dysregulated uremic host. [18][19][20] The mortality rate of CNE in the general population ranges from 7-32% [12,13] ; the outcome is even less optimistic in endocarditis patients with true negative blood culture than in patients with previous antibiotics treatment. [21] Furthermore, mortality is increased in patients receiving delayed treatment and in those still febrile after one week of therapy.…”