Staphylococcus argenteus as an etiological agent of prosthetic hip joint infection: a case presentation

Abstract

Abstract. This report presents a case of prosthetic hip infection caused by Staphylococcus argenteus, a potentially overlooked etiology of prosthetic joint infections (PJIs). Whole-genome sequencing showed that the S. argenteus isolate was an ST2250 and clustered within other CC2250 isolates, the largest clonal group of S. argenteus. This sequence type is prevalent and may be associated with invasive infections. The present isolate was phenotypically fully susceptible to all tested antimicrobial agents and genome analysis did not detect any resistance genes, nor were any staphylococcal cassette chromosome residues detected. Despite initial appropriate management with debridement and biofilm-active antibiotics, the outcome was unfavorable with recurrence and a persistent infection treated with suppressive antibiotics. Regarding the repertoire of genomic traits for virulence in S. argenteus, PJIs caused by this bacterium should be treated accordingly as Staphylococcus aureus PJIs.

Artritis séptica acromioclavicular por Staphylococcus argenteus. Reporte de un caso

“…Con respecto a las infecciones articulares por S. argenteus, solo hay un caso reportado de infección de la prótesis de cadera en Suecia. 8 Se plantearon diferentes posibilidades sobre el origen de la artritis, y la vía hematógena es la más probable, aunque no hay que descartar que una osteomielitis clavicular podría haber contaminado la articulación por contigüidad.…”

“…6 Las características clínicas de las infecciones por S. argenteus incluyen bacteriemia e infecciones de piel y tejidos blandos, aunque también hay un reporte de infección de la prótesis en la cadera. 7,8 En el momento de redactar este artículo, no hallamos antecedentes documentados de infecciones causadas por este patógeno en seres humanos, en Latinoamérica.…”

Description of Staphylococcal Strains from Straw-Coloured Fruit Bat (Eidolon helvum) and Diamond Firetail (Stagonopleura guttata) and a Review of their Phylogenetic Relationships to Other Staphylococci

“…Isolates assigned or re-assigned to this new species have been described in many countries including Australia ( Ng et al., 2009 ), Thailand ( Indrawattana et al., 2019 ; Pumipuntu, 2019 ), Laos ( Yeap et al., 2017 ), Cambodia ( Ruimy et al., 2009 ), Myanmar ( Aung et al., 2019 ), Japan ( Ohnishi et al., 2018 ; Aung et al., 2019 ; Kitagawa et al., 2020 ), China and Taiwan ( Chen et al., 2018 ), on Indian Ocean islands such as the Comoros or Mayotte ( Dupieux et al., 2015 ), Gabon ( Schuster et al., 2017 ), Trinidad and Tobago ( Monecke et al., 2014 ) and Brazil ( Rossi et al., 2020 ). Sporadic isolates also have been identified in the United Arab Emirates ( Senok et al., 2020 ), several European countries ( Dupieux et al., 2015 ; Rigaill et al., 2018 ; Tång Hallbäck et al., 2018 ; Diot et al., 2020 ; Kukla et al., 2020 ; Söderquist et al., 2020 ) as well as in Canada and the United States of America ( Eshaghi et al., 2021 ). These observations could be associated with travel and migration.…”

“…S. argenteus can asymptomatically be carried in the nares. It also can cause the same types of infections as S. aureus ( Becker et al., 2019 ), i.e., skin and soft tissue infections ( Ohnishi et al., 2018 ), osteomyelitis ( Rigaill et al., 2018 ) or endoprosthesis infections ( Diot et al., 2020 ; Söderquist et al., 2020 ) and sepsis ( Chen et al., 2018 ; Kitagawa et al., 2020 ). S. argenteus also has been implicated in food poisoning ( Suzuki et al., 2017 ).…”

Distribution of Virulence Factors and Resistance Determinants in Three Genotypes of Staphylococcus argenteus Clinical Isolates in Japan

“…In recent years, S. argenteus has been increasingly reported worldwide as an emerging pathogen, causing a wide spectrum of infectious diseases such as skin and soft-tissue infections (SSTIs) [ 6 , 13 ], necrotizing fasciitis [ 4 ], chronic prosthetic-related infection [ 25 , 26 , 27 ], bacteremia and invasive endovascular infections [ 14 , 19 , 28 ] that may have high impact of mortality [ 29 ]. It has also been documented as a nasal colonizing isolate in healthy people [ 30 ], an environmental isolate in dental clinics [ 31 ], and has even been identified in retail foods [ 32 ].…”