1942
DOI: 10.1001/jama.1942.02830350023006
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Staphylococcic Infection Simulating Scarlet Fever

Abstract: dysentery convalescents may have been partially due to the fact that the carriers of the two organisms were isolated within the same building. The stools of 2 patients (24 and 28), who were also recognized as typhoid carriers prior to the administration of sulfa¬ guanidine, continued positive for Eberthella. The drug failed to affect this organism, although the disappear¬ ance of the dysentery bacillus from the intestinal tract was prompt and apparently permanent. We have not yet attempted a deliberate trial w… Show more

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Cited by 63 publications
(11 citation statements)
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References 27 publications
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“…Exfoliatin is distinct from the alpha and delta toxins which are usually produced by human S. aureus strains. The reports of earlier investigators (1,3,4,8,9,10) claiming to demonstrate an erythrogenic toxin in culture supernatant fluids appear to have resulted from the presence of alpha toxin. These workers were able to destroy activity of supernatant fractions by heating at 56 to 61 C or neutralize activity with commercial antitoxin.…”
Section: Discussionmentioning
confidence: 93%
“…Exfoliatin is distinct from the alpha and delta toxins which are usually produced by human S. aureus strains. The reports of earlier investigators (1,3,4,8,9,10) claiming to demonstrate an erythrogenic toxin in culture supernatant fluids appear to have resulted from the presence of alpha toxin. These workers were able to destroy activity of supernatant fractions by heating at 56 to 61 C or neutralize activity with commercial antitoxin.…”
Section: Discussionmentioning
confidence: 93%
“…All cases met the Centers for Disease Control criteria for TSS (22). These TSS-associated strains included 11 isolates from Utah, 1 from Montana (EV1), and one from Idaho (LV1); these 13 strains were isolated in 1980. The remaining two vaginal isolates were NJ1 from Colorado, re- 0.003 0.003 0.0002 0.003 0.002 covered from patient 5 in the report by Todd et al presented as outpatients in Salt Lake City during 1980 (26), and the Harrisburg strain (20,21).…”
Section: Materias and Methodsmentioning
confidence: 99%
“…First, this organism was recovered from the vaginal fluid of all menses-related patients who had been appropriately cultured in one study (22). Second, there have been reports since 1927 of associations between clinical syndromes similar to TSS and S. aureus infections (1,9,25). Third, TSS has been reported to occur in males with localized S. aureus infections (5,8,26).…”
mentioning
confidence: 99%
“…However, the latter can generally be distinguished from Kawasaki's disease by the ( 1) epidemiology, (2) nature of the rash (which is generally maculopapular in Kawasaki's disease), (3) presence of notable hypotension, and (4) lack of lymph node enlargement. Rocky Mountain spotted fever, leptospirosis, and rubeola present with petechial or maculopapular rashes but generally have a different epidemiologic history.…”
Section: Differendal Diagnosismentioning
confidence: 99%