1976
DOI: 10.1097/00000658-197604000-00004
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Staphylococci in Community-acquired Infections. Increased Resistance to Penicillin

Abstract: One hundred patients with community-acquired staphylococcal infections of the skin and soft tissues were treated in the Emergency Ward of Cleveland Metropolitan General Hospital from June to October of 1974. Each staphylococcal infection was considered community-acquired if, within two weeks prior to being treated for the first time, the patient had not received antibiotics, had not been hospitalized, and had not been in contact with other recently hospitalized persons. Of 100 community-acquired staphylococcal… Show more

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Cited by 13 publications
(4 citation statements)
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“…A rising frequency of strains produ cing /2-lactamase, however, now also ap pears from sources outside the hospital en vironment [11,13,18,22]. The out-patient specimens of Bengtsson et al [6] exhibited a frequency of /2-lactamase producing strains similar to the proportion observed among our hospital strains.…”
Section: Discussionsupporting
confidence: 72%
“…A rising frequency of strains produ cing /2-lactamase, however, now also ap pears from sources outside the hospital en vironment [11,13,18,22]. The out-patient specimens of Bengtsson et al [6] exhibited a frequency of /2-lactamase producing strains similar to the proportion observed among our hospital strains.…”
Section: Discussionsupporting
confidence: 72%
“…By 1965, physicians and scientists felt that bacterial diseases and the microbes responsible were no longer of great concern. Unfortunately, it did not take too long for them to realize the existence of resistant bacteria [1][2][3], and by 1980, fewer than 10 % of all clinical Staphylococcus cases could be cured by penicillin-a dramatic shift from the almost 100 % susceptibility of Staphylococcus in 1952 [4,5]. To overcome this phenomenon of antibiotic resistance, scientists developed newer molecules with modified mechanisms of action.…”
Section: Introductionmentioning
confidence: 99%
“…Organisms such as methicillin-resistant Staphylococcus aureus (MRSA) and Coagulase Negative Staphylococci (CNS), and drug-esistant Enterobacteriaceae, as well as the emergence of multidrug-resistant bacteria, have created serious challenges to the treatment of infectious diseases including ocular infections. Moreover, the phenomenon of drug resistance is no longer restricted to hospital-acquired infections but is also being reported among community-acquired infections [5,10]. The situation is further complicated by the dearth of new antibiotics in the pipeline, raising the possibility that untreatable multi-drug resistant (MDR) infections will become more and more common [11,12].…”
Section: Introductionmentioning
confidence: 99%
“…Overall, 70% to 85% of strains found were penicillin-resistant (Hahn & Baker, 1980;Hughes, Chidi, & Macon, 1976;Ross et al, 1974).…”
Section: Penicillin-resistant Staphylococcus Aureus Staphylococcal Rmentioning
confidence: 99%