Staphylococcal Scalded Skin Syndrome in an Adult Patient with T-Lymphoblastic Non-Hodgkin’s Lymphoma

Abstract

Background: Staphylococcal scalded skin syndrome (SSSS) is an exfoliative dermatitis caused by Staphylococcus aureus infection. In contrast to infants, it is rarely observed in adults. SSSS in adults usually occurs in predisposed individuals such as those with renal failure or immunodeficiency, but has also been reported in otherwise healthy subjects. The reported mortality rate in adults is usually high because of serious underlying disease. Patient and Methods: We report a case of SSSS in a young female patient with T-lymphoblastic lymphoma, who survived this potentially lethal complication. Conclusions: To the best of our knowledge, this is the first case of SSSS in an adult patient with T-lymphoblastic non-Hodgkin’s lymphoma. Clinicians should be aware of SSSS as a rare but potentially fatal disorder, particularly in adult patients with malignancies undergoing aggressive chemotherapy.

Ritter Syndrome Mimicking Drug Eruption

“…The mortality rates are 5%, 30%, and between 40% and 60% in Stevens-Johnson syndrome, TEN, and SSSS, respectively (3)(4)(5)(6). Diagnosis is established clinically, but the most important parameter for confirmation is skin biopsy.…”

Toxic Epidermal Necrolysis Related to Cisplatin and Pemetrexed for Metastatic Non-Small Cell Lung Cancer

“…Staphylococcal scarlet fever is clinically not distinguishablefromstreptococcalscarletfever,butisaccompanied by exsudative tonsillitis. Further differential diagnoses are pemphigus vulgaris, erythema exsudativum multiforme and bullouspemphigoidaswellasburnsandcongenitaldisorders [12,13]. Thereisnoobjectiveevidenceforanoptimaltreatmentof TEN.…”

Staphylococcal Scalded Skin Syndrome in a Child with Acute Lymphocytic Leukemia

“…There is an overall incidence of SSSS between 0.09 and 0.13 cases per 1 million inhabitants annually (2). The accurate incidence of SSSS in immune deficient population is not known, and it is supposed that it is very rare; only a few case reports particularly in adult patients have been reported (3).…”