Staphylococcal bullous impetigo in a neonate

Abstract

An otherwise healthy, full-term neonate presented at day 15 of life to the pediatric emergency with generalized papulo-pustular rash for 2 d. This was finally diagnosed as bullous impetigo caused by Staphylococcus aureus (S. aureus). The skin lesions decreased significantly after starting antibiotic therapy and drainage of blister fluid. There was no recurrence of the lesions on follow-up. This case of generalized pustular eruption due to S. aureus in a neonate is reported, as it poses a diagnostic dilemma and can have serious consequences if left untreated.

Maternal-Fetal Perinatal Transmission of Staphylococcal Infections: A Report of Two Neonates

“…e pathophysiology of staphylococcal skin and soft tissue infections is related to secretion of bacterial extracellular proteins and bacterial surface components [8]. Exfoliative toxins A and B induce massive increase of T lymphocytes that secrete lymphokines IL-1, IL-6, and TNF-alpha [9]. Exfoliative toxin A further leads to formation of blisters.…”

Infection: Bacteria, Spirochetes, Protozoa, and Infestation

“…On the other hand, bullous impetigo commonly occurs in the intertriginous areas of children aged 2-5 years [3]. Bullous impetigo is caused by S. aureus phage group II (80%), phage type 71 (60% of cases).…”

Microbiological safety of cosmetic products and potential risks for consumers

“…S. aureus je sastavni deo fiziološke mikrobiote, ali i najčešći uzrok purulentnih infekcija kože, uključujući bulozni impetigo kod novorođenčadi (engl. staphylococcal scalded skin syndrome, SSSS) (10,11). P. aeruginosa, Serratia liquefaciens i Candida parapsilosis, detektovani su u kozmetičkim kremovima za negu kože lica i tela.…”

“…(13). Kozmetički proizvodi mogu biti kontaminirani i vrstama Bacillus anthracis i Clostridium tetani (10). Senke za oči i maskare mogu biti kontaminirane Staphylococcus spp., P. aeruginosa i K. pneumoniae, kao i Micrococcus spp., Corynebacterium spp., Acinetobacter spp., Moraxella spp., Neisseria spp.…”