Standardized Sterile Kits for Preparation of<sup>99m</sup>Tc-Labelled Albumin, Macroalbumin, Iron Ascorbic Acid Complex, and Antimony Sulphide Colloid

Bruun, Per

doi:10.3109/00365517109095706

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Time-dependent Properties Of Some Stored Diagnostic Agents1

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1973

1978

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“…Merlin found that solutions of sodium thiosulfate used to prepare Tc-S colloid preserved well for over 2 months even at room temperature while iron-ascorbic acid did not keep well (106). Also antimony sulfide used for 99m Tc-colloid were stable for long periods (16). The stability of pyridoxylidene glutamate was found to be less than 2 weeks in the solution form, whereas it kept well up to 6 weeks in the lyophilized form (92).…”

Section: Time-dependent Properties Of Some Stored Diagnostic Agentsmentioning

confidence: 99%

Time-Dependent Characteristics of Sn-Complexes for Preparing 99mTc-Labelled Radiopharmaceuticals and their Bioavailabilities - a Review

Noronha¹

1978

Nuklearmedizin

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Section: Time-dependent Properties Of Some Stored Diagnostic Agentsmentioning

confidence: 99%

Time-Dependent Characteristics of Sn-Complexes for Preparing 99mTc-Labelled Radiopharmaceuticals and their Bioavailabilities - a Review

Noronha¹

1978

Nuklearmedizin

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Use of Technetium ( ^99m Tc) as a Bacterial Label in Lung Clearance Studies

1973

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The suitability of technetium ( 99m Tc), a gamma emitter, for labeling of Diplococcus pneumoniae in studies of lung bacterial clearance was examined. A killed bacterial slurry with high specific activity was obtained with a ferric ascorbate reducing system. Approximately 5.5% of radioactive counts dissociated from labeled bacteria in 6 h. Rats were exposed to a uniformly mixed aerosol of untagged, viable pneumococci and killed, 99m Tc-tagged pneumococci. The aerodynamic behavior of labeled and unlabeled pneumococci was similar. Viable bacterial counts and radioactive counts were determined in lung homogenates at intervals following exposure, and rates of bacterial killing and disappearance of radioactive counts were plotted. Radioactive counts did not increase in the liver during the period of observation, suggesting that the decrease in lung radioactivity represents mucociliary clearance and not release of isotope to the systemic circulation. The use of 99m Tc for bacterial labeling provides advantages of technical simplicity and personnel safety compared to the use of beta-emitting isotopes.

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Standardized Sterile Kits for Preparation of^99mTc-Labelled Albumin, Macroalbumin, Iron Ascorbic Acid Complex, and Antimony Sulphide Colloid

Cited by 2 publications

References 11 publications

Time-Dependent Characteristics of Sn-Complexes for Preparing 99mTc-Labelled Radiopharmaceuticals and their Bioavailabilities - a Review

Time-Dependent Characteristics of Sn-Complexes for Preparing 99mTc-Labelled Radiopharmaceuticals and their Bioavailabilities - a Review

Use of Technetium ( ^99m Tc) as a Bacterial Label in Lung Clearance Studies

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Standardized Sterile Kits for Preparation of99mTc-Labelled Albumin, Macroalbumin, Iron Ascorbic Acid Complex, and Antimony Sulphide Colloid

Cited by 2 publications

References 11 publications

Time-Dependent Characteristics of Sn-Complexes for Preparing 99mTc-Labelled Radiopharmaceuticals and their Bioavailabilities - a Review

Time-Dependent Characteristics of Sn-Complexes for Preparing 99mTc-Labelled Radiopharmaceuticals and their Bioavailabilities - a Review

Use of Technetium ( 99m Tc) as a Bacterial Label in Lung Clearance Studies

Contact Info

Product

Resources

About

Standardized Sterile Kits for Preparation of^99mTc-Labelled Albumin, Macroalbumin, Iron Ascorbic Acid Complex, and Antimony Sulphide Colloid

Use of Technetium ( ^99m Tc) as a Bacterial Label in Lung Clearance Studies