Standardized natural product cannabis in pain management and observations at a Canadian compassion society: a case report

Abstract

An adult Caucasian male with excruciating pains following multiple traumas was monitored, daily, over one year while managing chronic pain by self-administering quantifiable amounts of natural cannabis. Tetrahydrocannabinol, Cannabidiol, and Cannabinol were all measured in tinctures, capsules, smoke-able product plus some baked goods, prior to their administration. By allowing standardization, the subject was able to develop a daily regimen of pain management that was resistant to a battery of most patent analgesics.

<i>In Vitro</i> Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines

“…Induction of apoptosis by cannabinoids in prostate and colon cancer cells may be phosphatase dependent [14]. Our case studies confirmed cannabinoid (CB) efficacy in reducing muscle spasticity in multiple sclerosis [15], pain levels over a 12-month period [16] and Cannabis responsive head injury induced multiple disabilities [17].…”

Standardized cannabis in multiple sclerosis: a case report

“…An earlier publication on the effects of standardized cannabis and chronic pain management describes a similar tolerant response [2]. A phenomenon often witnessed at the Society is persons with Celtic genealogy require 3 -5 five times greater dosage than those of Middle European or other descent.…”

Standardized Cannabis and Pain Management

“…Indeed, Indica's tend to have higher levels of Cannabidiol (CBD), a cannabinoid with demonstrated powerful antiinflammatory action (26). Our studies using HPLC to quantify cannabinoid concentrations in standardized capsules finds that a ratio roughly 1:10 CBD:THC, works well for pain relief in an oral preparation at doses of 20 to 100 mg (depending on tolerance) THC, every four to six hours (21,22).…”

“…A very special thanks to John Berfelo who's courage in treating his chronic pain with cannabis inspired and lent to our first case study (21) and much of the research referred to in this text.…”

“…Celts will frequently start with 50 to 100 mg of www.intechopen.com THC without experiencing any of the effects of overdose, whereas Europeans will start with 20 to 40 mg of THC. We have recently reported two case studies (21,22) where the members being studied were both of Celtic origin, both dealing with pain issues and each required up to 500mg of THC as cannabis per day, to relieve their symptoms. Now how does one determine THC concentrations in cannabis buds that are to be smoked or even prepped into an oral dose?…”