Standardized in Vitro Measurement of Heat Flux and Diameter of Frozen Region for Cryosurgical Probes

Speetzen, R.; Proske, M.; Heschel, I.; Rau, G.

doi:10.1007/978-1-4613-0373-2_7

Cited by 1 publication

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“…Nevertheless, none of these three imaging modalities completely resolve temperature within the iceball and so the surgeon remains blind to the location of the critical isotherm. Experimental work by Lam et al (1998) and Speetzen et al (1996) has recently added to the understanding of thermodynamics about cryoprobes. However, a guess at the location and shape of the isotherms based upon the imaged iceball edge and the temperature and location of the probe(s) must still be relied upon (Rewcastle et al 1997.…”

Section: Introductionmentioning

confidence: 99%

A model for the time-dependent thermal distribution within an iceball surrounding a cryoprobe

et al. 1998

Phys. Med. Biol.

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The optimal cooling parameters to maximize cell necrosis in different types of tissue have yet to be determined. However, a critical isotherm is commonly adopted by cryosurgeons as a boundary of lethality for tissue. Locating this isotherm within an iceball is problematic due to the limitations of MRI, ultrasound and CT imaging modalities. This paper describes a time-dependent two-dimensional axisymmetric model of iceball formation about a single cryoprobe and extensively compares it with experimental data. Thermal histories for several points around a CRYOprobe are predicted to high accuracy (5 degrees C maximum discrepancy). A realistic three-dimensional probe geometry is specified and cryoprobe temperature may be arbitrarily set as a function of time in the model. Three-dimensional temperature distributions within the iceball, predicted by the model at different times, are presented. Isotherm locations, as calculated with the infinite cylinder approximation, are compared with those of the model in the most appropriate region of the iceball. Infinite cylinder approximations are shown to be inaccurate when applied to this commercial probe. Adopting the infinite cylinder approximation to locate the critical isotherm is shown to lead the user to an overestimate of the volume of target tissue enclosed by this isotherm which may lead to incomplete tumour ablation.

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Section: Introductionmentioning

confidence: 99%

A model for the time-dependent thermal distribution within an iceball surrounding a cryoprobe

et al. 1998

Phys. Med. Biol.

View full text Add to dashboard Cite

show abstract

Standardized in Vitro Measurement of Heat Flux and Diameter of Frozen Region for Cryosurgical Probes

Cited by 1 publication

References 5 publications

A model for the time-dependent thermal distribution within an iceball surrounding a cryoprobe

A model for the time-dependent thermal distribution within an iceball surrounding a cryoprobe

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