Standardized ileal digestible valine:lysine dose response effects in 25- to 45-kg pigs under commercial conditions

Gonçalves, M. A. D.; Tokach, Mike D; Dritz, S. S.; Bello, Nora M.; Touchette, K. J.; Goodband, Robert D.; DeRouchey, Joel M.; Woodworth, J. C.

doi:10.1093/jas/skx059

Cited by 5 publications

(3 citation statements)

References 13 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the current study, the appropriate Lys requirement was estimated with a linear-break point model and a quadratic model using ADG and F:G as the response criteria. Noteworthy, we noticed that different statistical models could yield different requirement estimates, in accordance with previous studies [22][23][24]. Based on broken-line models, the dietary SID Lys levels for the minimum F:G was 0.88%, lower than the NRC [13] recommendations of 0.94% for 30 to 60 kg growing pigs.…”

Section: Discussionsupporting

confidence: 87%

Optimal dietary standardized ileal digestible lysine level for pigs during the grower, early and late finisher periods

Song

et al. 2022

BMC Vet Res

View full text Add to dashboard Cite

Background Lysine (Lys) is the first limiting amino acid for pigs fed corn-soybean meal diets. Three experiments were conducted to estimate the optimal standardized ileal digestible (SID) Lys requirement for growing (Exp. 1), early finishing (Exp. 2), and late finishing (Exp. 3) pigs under commercial conditions. Results and conclusions In Exp. 1, a total of 650 growing pigs (32.21 ± 0.33 kg bodyweight), were allocated to 5 dietary treatments supplemented with 0.75, 0.85, 0.94, 1.03, and 1.13% SID Lys. Each treatment had 5 replicate pens with 26 pigs per pen. The lowest feed to gain ratio (F:G) was obtained by pigs fed the 1.03% Lys diet and F:G showed both a linear and a quadratic response with increasing Lys (P < 0.05). Based on broken-line and quadratic analysis models, dietary SID Lys levels for the minimum F:G were 0.94%. In Exp. 2, 650 finishing pigs (57.24 ± 2.00 kg bodyweight) were allotted to 5 dietary treatments providing SID Lys of 0.63, 0.71, 0.79, 0.87, and 0.95%. Each treatment had 5 replicates, 26 pigs per replication. The highest final bodyweight was achieved by 0.79% Lys while the highest average daily gain (ADG) and average daily feed intake (ADFI) was achieved by pigs consuming the 0.87% Lys diet (P < 0.05). Additionally, the lowest F:G was obtained by pigs fed the 0.79 and 0.87% Lys diet (P < 0.05). Based on broken-line and quadratic analysis models, the optimum Lys was 0.81 and 0.82% for ADG and F:G, respectively. In Exp. 3, 600 late finishing pigs (92.22 ± 2.41 kg bodyweight), were divided into 5 treatments providing Lys levels of 0.53, 0.60, 0.66, 0.73, and 0.79%. Each treatment had 5 replicates, 24 pigs per replication. Results showed that final bodyweight, ADG, ADFI, and F:G was not affected by increasing dietary Lys level, suggesting that the lowest SID Lys (0.53%) was sufficient for this group of pigs. Taken together, the SID Lys requirement for pigs from 30 to 60 kg, 60 to 90 kg, 90 to 120 kg was 0.94%, 0.81 to 0.82, and 0.53%, respectively, depending on the response criteria with performance maximized.

show abstract

Section: Discussionsupporting

confidence: 87%

Optimal dietary standardized ileal digestible lysine level for pigs during the grower, early and late finisher periods

Song

et al. 2022

BMC Vet Res

View full text Add to dashboard Cite

show abstract

“…This can be due to reduced FI, increased EE and altered metabolism of BCAA and gut microbiota composition in pigs fed with VLP diets 33 . Although previous research has provided evidence on beneficial effects of supplemental BCAA on growth of nursery and growing pigs fed with diets with normal 31 , 32 or slightly low protein content 19 , 22 , 23 , 25 – 30 , 39 diets, little is understood whether supplementing VLP diets with BCAA can partially or completely recover the VLP induced depression of growth performance. In the current study, supplementing VLP diets with BCAA at levels recommended by Nutrient Requirements of Swine 8 delayed the onset of reduction in BW in nursery pigs.…”

Section: Discussionmentioning

confidence: 99%

“…Dietary deficiency of valine decreased the average daily feed intake (ADFI) and growth performance of weaned pigs 17 and supplementing slightly protein deprived diets with isoleucine and valine protected nursery and growing pigs against reduction in feed intake (FI) and body weight (BW) 7 , 19 , 28 – 30 . Further, the average daily gain (ADG) was increased with increasing the standard ileal digestibility (SID) valine:lysine in standard protein diets of nursery 31 and growing pigs 32 . Thus, previous research provides evidence on beneficial effects of supplemental BCAA on growth of pigs fed with diets with normal or slightly low protein content.…”

Section: Introductionmentioning

confidence: 99%

Effect of very low-protein diets supplemented with branched-chain amino acids on energy balance, plasma metabolomics and fecal microbiome of pigs

Spring

Premathilake

Bradway

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Feeding pigs with very-low protein (VLP) diets while supplemented with limiting amino acids (AA) results in decreased growth. The objective of this study was to determine if supplementing VLP diets with branched-chain AA (BCAA) would reverse the negative effects of these diets on growth and whether this is associated with alterations in energy balance, blood metabolomics and fecal microbiota composition. Twenty-four nursery pigs were weight-matched, individually housed and allotted into following treatments (n = 8/group): control (CON), low protein (LP) and LP supplemented with BCAA (LP + BCAA) for 4 weeks. Relative to CON, pigs fed with LP had lower feed intake (FI) and body weight (BW) throughout the study, but those fed with LP + BCAA improved overall FI computed for 4 weeks, tended to increase the overall average daily gain, delayed the FI and BW depression for ~ 2 weeks and had transiently higher energy expenditure. Feeding pigs with LP + BCAA impacted the phenylalanine and protein metabolism and fatty acids synthesis pathways. Compared to CON, the LP + BCAA group had higher abundance of Paludibacteraceae and Synergistaceae and reduced populations of Streptococcaceae, Oxyphotobacteria_unclassified, Pseudomonadaceae and Shewanellaceae in their feces. Thus, supplementing VLP diets with BCAA temporarily annuls the adverse effects of these diets on growth, which is linked with alterations in energy balance and metabolic and gut microbiome profile.

show abstract

Impact of increasing standardized ileal digestible valine: lysine in diets containing 30% dried distiller grains with solubles on growing pig performance

Clizer¹,

Tostenson²,

Tauer³

et al. 2022

Journal of Animal Science

View full text Add to dashboard Cite

A total of 2,430 pigs (DNA 600 x Topigs Norsvin 70, initially 39.4 kg) were used in a 28-d trial to determine the standardized ileal digestible (SID) Val:Lys requirement for pigs fed diets containing 30% DDGS. Treatments included 5 diets containing 30% DDGS with SID Val:Lys ratios of 60, 65, 70, 75, and 80%, plus a corn soybean meal (SBM) diet, for a total of 6 dietary treatments. Diets were formulated to be isocaloric through the inclusion of fat and to contain equal amounts of SID Lys within phase. Pens were assigned to dietary treatment in a randomized complete block design with initial body weight (BW) as the random blocking factor. Each dietary treatment was replicated 15 times and pens contained 27 pigs, balanced for sex. Increasing the SID Val:Lys ratio in diets containing 30% DDGS increased (Quadratic; P< 0.007) 14-d BW, final BW, average daily gain (ADG), average daily feed intake (ADFI) and gain:feed (G:F) for all periods. Providing a SID Val:Lys ratio of 75% resulted in the heaviest 14-d BW and final BW as well as greater ADG and ADFI of pigs fed 30% DDGS for all periods. The G:F response was maximized when a SID Val:Lys ratio of 70% was provided from d 0 to 14 while a SID Val:Lys ratio of 75% maximized G:F from d 14 to 28 and for the cumulative period. The SID Val:Lys requirement was estimated at 66.6% (95% CI:[65.9, 67.4]), 65.7 (95% CI:[64.8, 66.5]), and 68.4% (95% CI:[66.0, 70.8]) for ADG, ADFI, and G:F, respectively, using the straight broken line (SBL) method and 69.9% (95% CI:[68.2, 71.5]), 67.6 (95% CI:[65.4, 69.8]), and 72.8% (95% CI:[69.8, 75.8]) for the quadratic broken line (QBL) method. Pigs fed the corn-SBM diet had heavier 14-d BW, final BW, and greater ADG, ADFI, G:F (P< 0.032) compared to pigs fed diets containing 30% DDGS, except for cumulative ADFI compared to pigs receiving 75% SID Val:Lys (P = 0.167). In conclusion, these results suggest that when feeding 30% DDGS during the growing period, a SID Val:Lys ratio of 68% would yield more than 99% and 97% of the maximum ADG and G:F response for the 39 to 68 kg pig. However, growth performance of pigs fed diets containing 30% DDGS did not equate to pigs consuming the corn-SBM diet regardless of SID Val:Lys ratio.

show abstract

Standardized ileal digestible valine:lysine dose response effects in 25- to 45-kg pigs under commercial conditions

Cited by 5 publications

References 13 publications

Optimal dietary standardized ileal digestible lysine level for pigs during the grower, early and late finisher periods

Optimal dietary standardized ileal digestible lysine level for pigs during the grower, early and late finisher periods

Effect of very low-protein diets supplemented with branched-chain amino acids on energy balance, plasma metabolomics and fecal microbiome of pigs

Impact of increasing standardized ileal digestible valine: lysine in diets containing 30% dried distiller grains with solubles on growing pig performance

Contact Info

Product

Resources

About