Standardized Extract from the Gotu Kola Leaves Improves Suicidal Behavior in Stressed Rats Subjected to Social Isolation
Prasad Arvind Thakurdesai,
Savita Raju Nimse,
Padmaja Santosh Kore
et al.
Abstract:The leaves of Centella asiatica L. Urban (C. asiatica) and their bioactive compounds, triterpenoids asiaticoside (AS) and madecassoside (MA), are effective in reducing psychological stress and associated behavioral disorders in the conducted in vivo research. The present study evaluated AS+MA-based standardized C. asiatica leaves extract (INDCA) on SIS-induced suicidal behavior-related traits in laboratory rats. Male rats (n=6) were randomized, grouped, and individually caged for seven days for stress inductio… Show more
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