Standardization of an Efficient Experimental Gestational Diabetes Protocol
Fernanda Naves Araújo do Prado Mascarenhas,
Maria Júlia Neves Ribeiro,
Natália Ferreira Silva
et al.
Abstract:Diabetes mellitus (DM) is characterized by a dysfunction in insulin secretion and/or action which causes hyperglycemia. When the disease occurs during pregnancy, it is called gestational diabetes mellitus (GDM), and hyperglycemia affects the fetus's development. The present study aimed to standardize an efficient model of GDM induction in Wistar rats using streptozotocin (STZ). Therefore, the animals are placed for mating overnight, and the next day the presence of sperm is verified in the vaginal wash, indica… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.