Standardization and definitions in lower urinary tract dysfunction in children

Nørgaard, Jens Peter; Gool, Jan D. van; Hjälmås, K; Djurhuus, Jens Christian; Hellström, Anna‐Lena

doi:10.1046/j.1464-410x.1998.00025.x

Cited by 357 publications

(209 citation statements)

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“…According to the International Children's Continence Society [3], enuresis is defined as normal voiding occurring at a socially inappropriate time and place, in children aged >5 years. NE is voiding in bed without awakening; monosymptomatic NE is defined as enuresis with no daytime symptoms.…”

Section: Introductionmentioning

confidence: 99%

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Does monosymptomatic enuresis exist? A molecular genetic exploration of 32 families with enuresis/incontinence

Loeys

Hoebeke²,

Raes³

et al. 2002

BJU International

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Objectives To confirm linkage to microsatellite markers on chromosome 8q, 12q, 13q and 22q in families with nocturnal enuresis/incontinence segregating with an autosomal dominant pattern, and to determine if there is an association between the clinical subtype and these linked loci. Patients and methods Families with at least three members with nocturnal enuresis in two generations were included in the study. The index patient was 7 years old and had evidence of bladder dysfunction; all other family members were 5 years old. Bladder dysfunction in the index patients was documented by video‐urodynamics when indicated. A nycthemeral rhythm of diuresis was documented in all index patients. The clinical diagnosis of all family members was based on a questionnaire on voiding problems and micturition habits, uroflowmetry, measurement of functional bladder capacity and nocturnal diuresis. Linkage was analysed using an autosomal dominant model with a gene frequency equal to 0.05 and a penetrance of 0.9. Results Thirty‐two families with nocturnal enuresis/incontinence (one with four, 25 with three and six with two generations) were included. The mean number of persons included per family was 10 and on average five members were symptomatic. Linkage of nocturnal enuresis to a region on chromosome 22q11 was found in nine families, to 13q13–14 in six and to 12q in four. There was no convincing evidence for linkage to chromosome 8q. Clinical findings in the proband and their family members with possible linkage to a given locus were heterogeneous, and hence no clear genotype/phenotype correlation could be postulated. Conclusion These findings support the hypothesis of the genetic and phenotypic heterogeneity of nocturnal enuresis/incontinence. Putative linkage was confirmed to the same chromosomal loci as in previous studies of ‘monosymptomatic’ enuresis and different phenotypes were linked to the same loci.

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Section: Introductionmentioning

confidence: 99%

“…The classical definition of monosymptomatic NE by the International Children's Continence Society [3] has several shortcomings. If daytime symptoms are present, it is evident that there is an underlying bladder dysfunction.…”

Section: Introductionmentioning

confidence: 99%

Does monosymptomatic enuresis exist? A molecular genetic exploration of 32 families with enuresis/incontinence

Loeys

Hoebeke²,

Raes³

et al. 2002

BJU International

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“…Patients were evaluated for signs and symptoms of urinary tract infection; and if present, the study was deferred until the infection subsided. The urodynamic investigation was performed in accordance with the International Continence Society standards, [6] using Phoenix Griffon (Albyn Medical) V 2.04V interactive computer-based machine. A single operator performed the study, and intravenous midazolam (0.05-0.1 mg/kg body weight) sedation was used for uncooperative children.…”

Section: Introduction Materials and Methodsmentioning

confidence: 99%

“…again evaluated clinically and subjected to UDS for The incidence of lower urinary tract dysfunction for evidence of any postoperative neurovesical dysfunction. the different surgical techniques has been reported as The terminology recommended by the International 10.4% following Swenson's, 14.3% following Duhamel's Children's Continence Society [6] was used in evaluating procedure and 15.3% following Soave's procedure. [4,5] It and comparing the results.…”

Section: Introduction Materials and Methodsmentioning

confidence: 99%

Assessment of lower urinary tract function in children before and after Swenson′s ′pull through′ for Hirschsprung′s disease

Jindal

Grover

Bhatnagar

2007

J Indian Assoc Pediatr Surg

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Aims: Long-term sequelae in children with Hirschsprung's disease (HD) are usually related to abnormalities in defecation. However, some of these patients also suffer from voiding dysfunction. The aim of this study is to assess and define the effects of Swenson's 'pull through' procedure in patients with HD on lower urinary tract function by means of urodynamic studies (UDS) performed before and after surgery. Materials and Methods: Six patients with Hirschsprung's disease underwent UDS before and after the definitive procedure. Parameters observed were maximum cystometric capacity, compliance, unstable detrusor contraction (UDCS), leak point pressure, residual volume, end filling pressure, volume at Pdet <20 cm H 2 O and volume at Pdet <30 cm H 2 O. Results: On UDS evaluation, one patient (16.6%) showed a small-capacity bladder and one patient (16.6%) showed a large-capacity bladder with occasional uninhibited detrusor contraction (UDCS) preoperatively. All the children had good compliant bladders. Postoperatively, one child was clinically symptomatic and showed hyporeflexic large-capacity bladder without any UDCS, one patient showed a small-capacity bladder with UDCS. Conclusions: In Hirschsprung's disease, neurovesical dysfunction may exist preoperatively and though the incidence of postoperative changes in neurovesical function may appear high, a larger study is required for statistical validation. Children who present with urinary problems after surgery should be assessed urodynamically.

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“…São caracterizados como: aumento ou diminuição da frequência miccional, incontinência, urgência, noctú-ria, hesitação, esforço, jato fraco, jato intermitente, manobras de contenção, sensação de esvaziamento incompleto, gotejamento pós-miccional, dor genital ou do trato urinário inferior. 29 Adiamento da micção: Crianças com incontinência diurna adiam a micção usando manobras de contenção, quadro que, geralmente, se associa com baixa frequência miccional e sensação de urgência com a bexiga cheia. Estas crianças frequentemente sofrem de comorbidade psicológicas ou distúrbio de comportamento.…”

Section: Epidemiologiaunclassified

Lower urinary tract dysfunction - a common diagnosis in the pediatrics practice

Vasconcelos¹,

Lima²,

Vaz

et al. 2013

Jornal Brasileiro De Nefrologia

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. Pró -Reitoria de Pesquisa da UFMG, FAPEMIG -Fundação de Apoio à Pesquisa de Minas Gerais -e CNPq -Conselho Nacional de Pesquisa.Disfunção do trato urinário inferior indica uma função anormal do trato urinário inferior para a idade da criança, que pode levar à perda da capacidade coordenada de armazenamento e eliminação de urina. É uma entidade comum em crianças, embora subdiagnosticada na prática clínica, e que, além de representar um risco para o trato urinário superior, causa um constrangimento emocional aos pais e às crianças, devido à incontinência urinária e à frustração em lidar com o problema. A aquisição da continência urinária diurna ocorre na maioria das crianças até os 4 anos e a noturna até os 5 anos de idade. Após esta idade, a incontinência urinária torna-se um problema social. Apesar da importância clínica, muitas vezes, os pais desconhecem os sintomas dessa disfunção. Esse artigo tem como objetivo abordar os principais aspectos relacionados ao diagnóstico dessa disfunção. IntroduçãoA incontinência urinária diurna em crianças na idade escolar não é uma queixa valorizada pela maioria das famílias, não sendo, portanto, determinante para motivar uma consulta médica. 1 A Disfunção do Trato Urinário Inferior (DTUI) é investigada e comumente diagnosticada após episódios de infecção do trato urinário 2 ou quando a criança também apresenta enurese. 3 Enurese é o termo utilizado para a perda urinária durante o sono em crianças acima de 5 anos de idade. Ela pode apresentar-se como um sintoma isolado (enurese monossintomática) ou vir Lower urinary tract dysfunction indicates an abnormal function of the lower urinary tract to the child's age, which can lead to loss of coordinated capacity storage and elimination of urine. It is a common entity in children, although underdiagnosed in clinical practice, and that, besides representing a risk to the upper urinary tract, causes an emotional embarrassment to parents and children, due to urinary incontinence and frustration in dealing with the problem. The acquisition of daytime urinary continence occurs in most children until age 4 and night, until 5 years of age. After this age, urinary incontinence becomes a social problem. Despite the clinical importance often parents are unaware of the symptoms of this dysfunction. This article aims to address the key issues related to the diagnosis of this dysfunction. Disfunção do trato urinário inferior -um diagnóstico comum na prática pediátricaLower urinary tract dysfunction -a common diagnosis in the pediatrics practice resumo AbstrActPalavras-chave: diagnóstico, incontinência urinária, pediatria.Keywords: diagnosis, urinary incontinence, pediatrics.acompanhada de sintomas do trato uriná-rio inferior (tais como, urgência miccional, aumento ou diminuição da frequên-cia urinária e alterações do jato urinário) 3 sendo, então, denominada enurese não monossintomática. Nota-se que a DTUI nem sempre é evidente e, muitas vezes, só é diagnosticada após lesões irreversíveis do trato urinário superior. 2 O diagnóstico precoce e a ...

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Standardization and definitions in lower urinary tract dysfunction in children

Cited by 357 publications

References 13 publications

Does monosymptomatic enuresis exist? A molecular genetic exploration of 32 families with enuresis/incontinence

Does monosymptomatic enuresis exist? A molecular genetic exploration of 32 families with enuresis/incontinence

Assessment of lower urinary tract function in children before and after Swenson′s ′pull through′ for Hirschsprung′s disease

Lower urinary tract dysfunction - a common diagnosis in the pediatrics practice

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