2012
DOI: 10.1111/j.1749-4486.2012.02502.x
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Staging primary middle ear cholesteatoma with non‐echoplanar (half‐Fourier‐acquisition single‐shot turbo‐spin‐echo) diffusion‐weighted magnetic resonance imaging helps plan surgery in 22 patients: Our experience

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Cited by 25 publications
(12 citation statements)
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“…However, as reported in other studies [1,18,23,24], the main limitation of CT is the low specificity for cholesteatoma when tissue is present in the tympanic and mastoid air cavity because it cannot differentiate between cholesteatoma, cholesterol granuloma, brain parenchyma, granulation and scar tissue, just as in our experience (with a sensitivity of only 56%). It is typically the case of an FN patient whose CT scan showed no erosion signs, while both EPI and not-EPI DWI-MR revealed the presence of cholesteatoma confirmed also during surgery (fig.…”
Section: Discussionmentioning
confidence: 53%
“…However, as reported in other studies [1,18,23,24], the main limitation of CT is the low specificity for cholesteatoma when tissue is present in the tympanic and mastoid air cavity because it cannot differentiate between cholesteatoma, cholesterol granuloma, brain parenchyma, granulation and scar tissue, just as in our experience (with a sensitivity of only 56%). It is typically the case of an FN patient whose CT scan showed no erosion signs, while both EPI and not-EPI DWI-MR revealed the presence of cholesteatoma confirmed also during surgery (fig.…”
Section: Discussionmentioning
confidence: 53%
“…Cholesterol granuloma is often seen as a round mass with defined border in CT scan which can be isodense, slightly hyperdense, or mixed. Cholesteatoma is displayed as a soft hemogenic tissue with bone degeneration in CT scan [ 6 ]. In MRI, Cholesterol granuloma generates a high signal in both T1 and T2 imaging which is enhanced after introducing contrast.…”
Section: Discussionmentioning
confidence: 99%
“…Given the high diagnostic performance of non-echoplanar diffusion-weighted MRI, it is currently the modality of choice in detecting post-operative cholesteatoma and has been applied as an adjunct to CT in the assessment of primary cholesteatoma. 3 Diffusion-weighted MRI also performs well in depicting the size and extent of cholesteatoma. 45 However, bony anatomy is lacking on diffusion-weighted MRI, meaning precise disease localisation is challenging when planning surgery.…”
Section: Introductionmentioning
confidence: 99%
“…2 Diffusion-weighted magnetic resonance imaging (MRI), specifically non-echoplanar diffusion-weighted MRI, can reliably characterise cholesteatoma and differentiate it from soft tissue and fluid within the middle-ear cleft. 13 This is because cholesteatoma, by virtue of its keratin content, has high signal intensity on diffusion-weighted MRI images (b-value of 800 or 1000) due to a combination of restricted diffusion and T2 shine-through effect.…”
Section: Introductionmentioning
confidence: 99%