“…7 The introduction of microsurgical techniques and electrophysiological monitoring has improved the anatomical and functional preservation of the facial and vestibulocochlear nerves. 13 The primary goal of vestibular schwannoma surgery has changed from preserving the patient's life to preserving their neurological function. 14 In 1979, Cohen was one of the first to report the outcome of surgery using the retromastoid approach aimed at hearing preservation: 8 per cent facial nerve paralysis and no reported mortality.…”
Section: Discussionmentioning
confidence: 99%
“…The operative mortality rate for vestibular schwannoma has dropped dramatically, from 40 per cent at the beginning of the last century to less than 1–2 per cent in the past decade 7 . The introduction of microsurgical techniques and electrophysiological monitoring has improved the anatomical and functional preservation of the facial and vestibulocochlear nerves 13 . The primary goal of vestibular schwannoma surgery has changed from preserving the patient's life to preserving their neurological function 14 …”
The retromastoid, suboccipital surgical approach to the skull base can be safely and successfully achieved using a microsurgical technique, with minimal or no damage to neurovascular structures, even for large tumours.
“…7 The introduction of microsurgical techniques and electrophysiological monitoring has improved the anatomical and functional preservation of the facial and vestibulocochlear nerves. 13 The primary goal of vestibular schwannoma surgery has changed from preserving the patient's life to preserving their neurological function. 14 In 1979, Cohen was one of the first to report the outcome of surgery using the retromastoid approach aimed at hearing preservation: 8 per cent facial nerve paralysis and no reported mortality.…”
Section: Discussionmentioning
confidence: 99%
“…The operative mortality rate for vestibular schwannoma has dropped dramatically, from 40 per cent at the beginning of the last century to less than 1–2 per cent in the past decade 7 . The introduction of microsurgical techniques and electrophysiological monitoring has improved the anatomical and functional preservation of the facial and vestibulocochlear nerves 13 . The primary goal of vestibular schwannoma surgery has changed from preserving the patient's life to preserving their neurological function 14 …”
The retromastoid, suboccipital surgical approach to the skull base can be safely and successfully achieved using a microsurgical technique, with minimal or no damage to neurovascular structures, even for large tumours.
“…In the literature there are evidence of two-stage resections for giant vestibular schwannomas but in those cases the second operation was either by a different route [9] or after a gap of at least a couple of weeks. [20] Our study is unique in the sense that the second operation was performed on the very next day and complete resection was achieved without adding any morbidity and mortality.…”
Section: Discussionmentioning
confidence: 99%
“…There are studies with 1-to 2-month interval between the stages. [9] The practice of pre-operative embolization of the tumor and definitive surgery 1 to 2 months later appears to be a viable option, but due to economical and logistical constraints in our set up it is more often than not, practically unfeasible. [10] We present a series of 12 cases of giant vestibular schwannomas which were operated upon in two stages on two consecutive days in a government institute which although a tertiary referral centre for this area does lack advanced neurosurgical equipments like ultrasonic aspirator and nerve monitoring facilities.…”
Introduction: Vestibular schwannomas constitute 8% of all intracranial tumors. A majority of vestibular schwannomas are sporadic and unilateral. Giant vestibular schwannomas are seen in our country due to the late diagnosis and long duration of symptoms before diagnosis. These giant schwannomas are challenging to manage as most of the patients are having brainstem compression. Materials and Methods: Twelve cases of a giant vestibular schwannoma were operated in our department between May 2011 and December 2012. Vestibular schwannomas with a maximal diameter of more than 4 cm were defined as a giant vestibular schwannoma. All the patients had a unilateral vestibular schwannoma. Performance status of all the patients were graded as per the Karnofsky performance score. Pre-operative assessment of 5 th , 7 th , 8 th and lower cranial nerve status was done in all cases. Ventriculoperitoneal shunting was done pre-operatively in all cases. All patients were operated through retromastoid suboccipital craniectomy and retrosigmoid approach. These patients were operated in two stages in two consecutive days with overnight elective ventilation in ICU. Ultrasonic aspirator and nerve monitoring techniques were not used. Results: Giant acoustic schwannomas can be safely resected completely by a staged resection on two consecutive days without any increased morbidity or mortality. This technique may be employed to achieve complete resection of such lesions without deterioration of facial nerve function in institutions which do not have advanced facilities like nerve monitoring or ultrasonic aspirator.
“…Very recently, a few studies have tried to prepare polybenzoxazine nanofibres by the electrospinning procedure. [34][35][36][37][38][39] When subjected to heat treatment, however, the polymerization of the oxazine ring in the electrospun fibre phase probably led to surface crosslinking and coalescence of neighbouring nanofibres. Therefore, preventing aggregation of individual nanofibers during carbonization is a critical challenge in constructing the morphology of 1D electrospun structures.…”
Polynaphthoxazine-based 1D carbon nano-materials were fabricated by a single-nozzle electrospinning process in a mixed polymer solution followed by curing and carbonization.
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