“…In experimental fractures, the musculature constitutes the basis for vessel sprouting into the fracture exudate, and treatment of severe fractures demonstrates the importance of soft-tissue coverage (Gothman et al 1961, Edwards et al 1983. Nather et al (1990) showed that in nonvascularized diaphyseal transplants, the bones isolated from their vascular muscle bed were impaired in terms of fracture healing.…”