Staged excision versus Mohs micrographic surgery for lentigo maligna and lentigo maligna melanoma

Walling, Hobart W.; Scupham, Richard K.; Bean, Andrew; Ceilley, Roger I.

doi:10.1016/j.jaad.2007.02.011

Cited by 131 publications

(111 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Various techniques to achieve complete histologic margin control have been described including, but not limited to permanent section total peripheral margin control and Mohs micrographic surgery. 49,50,[104][105][106] No prospective randomized data are available to make specific recommendations. However, referral for more exhaustive histologic margin assessment may be considered when extensive subclinical extension is suspected.…”

Section: Surgical Managementmentioning

confidence: 99%

Guidelines of care for the management of primary cutaneous melanoma

Bichakjian

Halpern

Johnson

et al. 2011

Journal of the American Academy of Dermatology

413

269

View full text Add to dashboard Cite

Section: Surgical Managementmentioning

confidence: 99%

Guidelines of care for the management of primary cutaneous melanoma

Bichakjian

Halpern

Johnson

et al. 2011

Journal of the American Academy of Dermatology

413

269

View full text Add to dashboard Cite

“…Suspected recurrences were confirmed by biopsy. Gross tumor and surgical defect sizes were calculated as previously described 8,9 by averaging the measured length and width and approximating the area by using the formula pr 2 to calculate the area of a circle with the diameter equal to the above average.…”

Section: Methodsmentioning

confidence: 99%

Modified Mohs Micrographic Surgery for Periocular Melanoma and Melanoma In Situ: Long-Term Experience at Scripps Clinic

Shumaker¹,

Kelley

Swann³

et al. 2009

Dermatologic Surgery

View full text Add to dashboard Cite

show abstract

“…They noted a significantly higher recurrence risk with MS than with staged excision, 33 versus 7.3%, respectively. However, they performed MS without immunostaining and their sample size for MS was only 18 patients [71].…”

Section: Local Recurrence Riskmentioning

confidence: 99%

Mohs surgery for melanoma: rationale, advances and possibilities

Etzkorn

Cherpelis

Glass

2011

Expert Review of Anticancer Therapy

View full text Add to dashboard Cite

Mohs surgery (MS) is an effective technique for the removal of a variety of cutaneous neoplasms by virtue of its thorough assessment of margins. It has yet to become widely accepted for melanoma because recognizing melanocytes histologically in frozen section can be problematic. Recently, 'rapid' methods of immunohistochemistry have been developed that resolve this issue by staining the melanocytes in frozen section. In addition, some of the immunohistochemistry protocols that previously required up to 1 h now take 19 min or less. These technological enhancements for MS have removed some of the obstacles towards the acceptance of MS as a legitimate option for removal of melanomas, especially poorly demarcated lesions and lesions from the head and neck, the distal extremities and the genitalia. Experience thus far with MS for melanoma has shown lower recurrence rates and improved disease-specific survival compared with historical controls for standard excision, while at the same time minimizing the sacrifice of normal tissue.

show abstract

Staged excision versus Mohs micrographic surgery for lentigo maligna and lentigo maligna melanoma

Cited by 131 publications

References 31 publications

Guidelines of care for the management of primary cutaneous melanoma

Guidelines of care for the management of primary cutaneous melanoma

Modified Mohs Micrographic Surgery for Periocular Melanoma and Melanoma In Situ: Long-Term Experience at Scripps Clinic

Mohs surgery for melanoma: rationale, advances and possibilities

Contact Info

Product

Resources

About