Stage distribution of malignant melanomas in a Hungarian centre

Tóth, Veronika; Somlai, Beáta; Hársing, Judit; Hatvani, Zsófia; Kárpáti, Sarolta

doi:10.1556/oh.2013.29629

Cited by 1 publication

(2 citation statements)

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“…The stage distribution of PAM patients (stage I in 61.7 % and stage IV in 2.9 %) was almost the same as a previous study from our Department, which showed that the majority of the diagnosed melanomas were stage I (60.4 %) and just in 0.4 % of melanomas were detected in stage IV [28].…”

Section: Discussionsupporting

confidence: 85%

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Retrospective Analysis of Clinicopathological Characteristics of Pregnancy Associated Melanoma

Fábián

Tóth

Somlai

et al. 2015

Pathol. Oncol. Res.

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Pregnancy associated melanoma (PAM) by definition appears during pregnancy or within 1 year after delivery. In this retrospective study we analysed the pathological characteristics and survival rate of PAM and matched the data with non-pregnant age- and stage-matched control patients. Between 2003 and 2014, 34 pregnant women (aged 32.5 ± 5.6 years) were diagnosed with melanoma at the Department of Dermatology, Venereology and Dermatooncology of the Semmelweis University. During the pathological process histologic subtype, Breslow thickness and Clark level, tumor cell type, mitotic rate, peritumoral inflammation, as well as ulceration, regression, necrosis, vascular invasion and presence of satellite were analyzed and related to clinical data. Primary tumor location and clinical staging, disease course, local recurrence and metastases, 5-year survival rate, other tumor development before or after the diagnosis of melanoma have also been documented. We found no difference in all parameters between pregnant and non-pregnant melanoma cases except peritumoral inflammation which was higher in PAM group, moreover the presence of mild inflammation was significantly higher in PAM group compared to non-pregnancy associated melanoma (NPAM) women group.

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Section: Discussionsupporting

confidence: 85%

“…The mean age of women at melanoma diagnosis was 32.5 ± 5.6 years (min.-max. [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40]. Most PAMs (23/34, 67.6 %) were diagnosed at very early stages (2/34 (5.9 %) in situ melanoma, 21/34 (61.7 %) stage I melanoma).…”

Section: Temporal Relation and Clinical Staging Of Melanoma To Pregnancymentioning

confidence: 99%