Stage-based outcomes of 682 consecutive cases of twin–twin transfusion syndrome treated with laser surgery: the USFetus experience

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“…We note that Moise and his colleagues have not supplied us with their dual fetal survival prior to their adoption of the Solomon technique, but we are reasonably sure that it was very similar to that reported in our paper, and that reported by another USA center (50.7%) 5 . The surgeons who operated on the cases in our study were experienced and were not new to laser surgery 6 .…”

Fetoscopic Laser Photocoagulation for the Treatment of Twin-Twin Transfusion Syndrome in Monochorionic Twin Pregnancies

“…The Quintero stage did not worsen in any of the survivors; however, stage III atypical, which was defined as abnormal Doppler flow with visible donor bladder, had a decreased survival rate especially in 2 survivors. Table 4 presents the perinatal outcomes in published series including early series of pioneer operators [1,[17][18][19][20] and published data [12,[21][22][23][24]] from the conclusion of the Eurofetus trial comparison to the present study. Early series reported approximately a 60% overall survival rate, a 5% neurological complication rate; and a 40% survival rate of both twins.…”

“…Early series reported approximately a 60% overall survival rate, a 5% neurological complication rate; and a 40% survival rate of both twins. Middledorp et al [21], Cincotta et al [12], Huber et al [22], and Chmait et al [23] describe improved perinatal outcomes: > 70% overall survival, 58-69% with two survivors and; and > 80% with at least one survivor. Hecher et al and Huber et al reported the data from their 400 consecutive case series divided into two groups: the first 200 [20] and last 200 [22].…”

Current Treatment of Twin-to-Twin Transfusion Syndrome

“…Сравнивая данные этих исследований, частота вы-живаемости в группе ТАР составила 64,4% (78/121) по сравнению с 81,5% (137/168) в группе лазерной терапии (p=0,001). Отдаленная неврологическая заболеваемость в этих группах варьировала от 4,2 до 5,6% [14,15].…”

“…На этапе дебатов о потенциальной эффектив-ности двух подходов к лечению ФФТС группа Eurofetus провела рандомизированное контролиру-емое исследование, в котором сравнивали серий-ные амниоредукции и селективную ФЛК анасто-мозов плаценты [14]. Предварительный статисти-ческий анализ показал необходимость включения в исследование 172 пациенток, чтобы подтвердить значимые различия между двумя терапевтически-ми подходами.…”