Stage 3 perianal extra mammary Paget's disease: A case report of a non-operative approach

Perianal extramammary Paget’s disease with adenocarcinoma of perianal skin area, a case report

“…Multidisciplinary meetings are advisable for such a rare disease when evidence and guidelines for its management are lacking in order to discuss various suitable treatment modalities, such as chemotherapy and radiotherapy along with surgical intervention and topical management [ 3 ]. In our case, a multidisciplinary team was involved from the beginning and their recommendations have been followed to ensure best outcomes.…”

“…Paget disease was first described and named by Sir James Paget, who in 1874 described a skin lesion around the nipple that looked similar to eczema and had underlying breast malignancy potential [ 1 ]. Extramammary Paget disease (EMPD) is an uncommon and slow-growing skin adenocarcinoma that originates in the anogenital region and axilla outside the mammary glands [ 2 ], often in regions with apocrine glands [ 3 ]. The most common location for EMPD is the vulva, followed by perineal, perianal, scrotal and penile skin [ 4 ].…”

Extramammary Paget's Disease of the Vulva: A Rare Case Report

“…Extramammary Paget's Disease (EMPD) is a rare disease characterized by the involvement of nonsquamous carcinoma cells in the intraepithelial layer of the skin. 1 This disease most often occurs in areas containing apocrine glands such as the vulva, perineum, perianal area, scrotum, and penis. 2 Extramammary Paget's disease is relatively rare with a reported incidence ranging from 0.1 to 2.4 patients per 1,000,000 people per year.…”