Stable germline transgenesis using theMinosTc1/marinerelement in the sea urchin,Lytechinus pictus
Elliot W. Jackson,
Emilio Romero,
Svenja Kling
et al.
Abstract:Stable transgenesis is a transformative tool in model organism biology. While the sea urchin is one of the oldest animal models in cell and developmental biology, it has relied on transient manipulations of wild animals, and has lacked a strategy for stable transgenesis. Here we build on recent progress to develop a more genetically tractable sea urchin species, Lytechinus pictus, to establish a robust transgene integration method. Three commonly used transposons (Minos, Tol2, piggyBac) were tested for non-aut… Show more
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