Stabilized Hyaluronic Acid of Non-animal Origin for Rejuvenating the Skin of the Upper Arm

Rejuvenation of Periorbital Area: Treatment with an Injectable Nonanimal Non-Crosslinked Glycerol Added Hyaluronic Acid Preparation

“…3 In this study, our group tested the hypothesis that small amounts of HA of nonanimal origin, in association with glycerol, injected into the superficial dermis could reduce some of these signs of aging. 3 In this study, our group tested the hypothesis that small amounts of HA of nonanimal origin, in association with glycerol, injected into the superficial dermis could reduce some of these signs of aging.…”

“…3,5 After conducting bibliographic research covering the last 10 years, our group found no published studies on the hydration of the periorbital region using injectable HA, with or without glycerol. Other studies have shown favorable results when using HA for skin rejuvenation of the face or arms.…”

“…3 Therapeutic approaches in this region are not easy, principally because the anatomical structures are delicate and adverse events can occur even when every precaution is taken. In human skin, it helps support, lubricate, and absorb impacts.…”

Consensus Recommendations for Optimal Augmentation of the Asian Face with Hyaluronic Acid and Calcium Hydroxylapatite Fillers

“…35,36 Injecting small aliquots of hyaluronic acid into large areas of the dermis (e.g., covering both cheeks, the entire face, neck, or décolletage in intervals of 2 to 6 weeks over three treatment sessions) has been shown to gradually improve cutaneous hydration, leading to enhanced skin turgor and firmness, [37][38][39] improvement in skin surface roughness and elasticity, [37][38][39][40] and neosynthesis of collagen. [37][38][39][41][42][43] Small amounts of gel are administered using a semirandom micropuncture technique (Table 14). Initially, two or three treatment sessions in a 4-week interval are usually required for maximal improvement, with a maintenance schedule of one session every 4 to 6 months recommended for sustained improvement in skin quality.…”

Facial Soft-Tissue Fillers conference: Assessing the State of the Science

“…No unexpected or serious adverse events were reported, and all expected treatment-related adverse events including discomfort at the injection site, bruising, and hematoma were of mild intensity. 17 …”