Stabilized cationic dipeptide capped gold/silver nanohybrids: Towards enhanced antibacterial and antifungal efficacy

Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations

“…These findings was also accompanied with decrease concentration of polysaccharides, lipids, proteins, and nucleic acids in biofilm compared with controls [150]. The antimicrobial action resulting from conjugating cationic peptides on the surface of either gold or silver nanoparticles was evaluated [151]. The findings indicated that silver nanoparticles surface decorated with cationic peptide revealed higher antimicrobial efficiency relative to peptide decorated gold nanoparticles as well as undecorated metallic nanoparticles and native peptides.…”

Bioactive nano-metal–organic frameworks as antimicrobials against Gram-positive and Gram-negative bacteria

“…These formulations have shown increased bactericidal activity, allowing 2-to 10-fold lower dosage of antibiotic for an equivalent bactericidal effect. 76,77 These previous studies also suggest that nMOF/antibiotic combination therapy might be superior to that of monotherapy, with the advantage of a reduced dose requirement. [78][79][80] In some separate experiments, we have also tested some other nMOFs -NH 2 -MIL-53(Fe), MIL-53(Al), and NH 2 -UiO-66 (Zr)in combination with antibiotics; however, no significant additional antimicrobial activity was observed (data not shown).…”

Nano-Based Drug Delivery or Targeting to Eradicate Bacteria for Infection Mitigation: A Review of Recent Advances

“…The nanoparticles could bear the proteolytic digestion for protecting the peptide. Bajaj et al (2017) reported the development of antimicrobial dipeptide-stabilized Au or Ag nanohybrids. The Ag nanoparticles containing dipeptides showed MIC of 0.37-0.93 µM against S. aureus, whereas the Ag nanoparticles or dipeptides alone only exhibited the MIC of 2.47 or 24.16-50.83 µM.…”