Stabilization of red blood cell aggregation evaluation using short-axis view of vein of ultrasound

Abstract

Red blood cell (RBC) aggregation is the reversible adhesion of RBCs among themselves. We previously reported a positive correlation between blood glucose level and the degree of RBC aggregation (the brightness of the B-mode image). In the present study, we investigated the contribution to the brightness according to the deviation from the central axis in measurements along with the long-axis view of the vein. The results show that the brightness changed significantly for a slight change in the lateral position in the short-axis image. We found that the stability of the measurements was not guaranteed in the long-axis view and estimated the correct analysis window range for the short-axis view.

In vivo measurement of attenuation coefficient of blood in a dorsal hand vein in a frequency range of 10–45 MHz: A preliminary study

“…These measurements were approved by the Ethics Committee of the Graduate School of Engineering, Tohoku University, and all the participants agreed to participate in the present study. RF signals scattered from the lumen were obtained using ultrasonic short-axis measurements [29]. The focal depth d F of the probe was set at the center of the lumen.…”

Estimation of aggregate size of red blood cell by introducing reference power spectrum measured for hemispherical ultrafine wire

“…Moreover, in this study, the shortaxis scan was used for the measurement to reduce the effect of the elevational misalignment of vessels in the long-axis measurement. 36) In this measurement, the number of beams that can be used as the signals of the posterior wall is small, and the effect of the dip caused by the unwanted signals included in the analysis range of the posterior wall might not be removed. This might increase the fitting error of the conventional method.…”

“…We have studied a noninvasive and quantitative method for measuring blood properties. [28][29][30][31][32][33][34][35][36][37] Saito et al assumed that RBCs aggregate as a single-sphere scatterer and estimated the size from the scattering characteristics extracted by normalizing the power spectrum measured from the vessel lumen with that from the rear wall using a focused ultrasound transducer. [28][29][30][31][32] We also examined the relationship between RBC aggregation using ultrasound and blood glucose level.…”

“…Moreover, Fukase et al suggested that the effect of elevational misalignment of vessels in the long-axis measurement on the evaluation of the degree of RBC aggregation could be reduced by short-axis measurement. 36) However, in the short-axis measurement of the vessel, few beams can be used as the signal of the rear wall, making it difficult to remove the dips that appear on the averaged power spectrum. Therefore, robust size estimation using short-axis measurements could be difficult.…”

Enhancement of reflection and backscattering components by plane wave imaging for estimation of surface roughness

“…For these reasons, diagnostic ultrasound seems to be the most suitable technique for the diagnosis of atherosclerosis. [2][3][4] The following techniques are widely used in the diagnosis of atherosclerosis by means of ultrasound. Pulse wave velocity is an index representing arterial stiffness, which is obtained by measuring the pressure wave propagating along the artery.…”