Stabilization in early adult-onset myopia with corneal refractive therapy

González-Meijóme, José Manuel; Carracedo, Gonzalo; Lopes-Ferreira, Daniela; Faria‐Ribeiro, Miguel; Peixoto-de-Matos, Sofia C.; Queirós, António

doi:10.1016/j.clae.2015.06.009

Cited by 17 publications

(12 citation statements)

References 30 publications

(37 reference statements)

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“…A few studies suggest that early termination of OK treatment might lead to a greater increase in axial elongation and myopia in children, 61,78,79 although this has not been found to be the case in university students with adult-onset, progressive myopia. 80 Some studies also suggest that relative treatment efficacy may decrease with time. 75,81,82 Reduced treatment efficacy has been linked to lower baseline myopia, 69,[82][83][84] although there may be confounding factors not accounted for.…”

Section: Spectaclesmentioning

confidence: 99%

IMI – Interventions for Controlling Myopia Onset and Progression Report

Wildsoet

Chia

Cho

et al. 2019

Invest. Ophthalmol. Vis. Sci.

252

275

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Myopia has been predicted to affect approximately 50% of the world's population based on trending myopia prevalence figures. Critical to minimizing the associated adverse visual consequences of complicating ocular pathologies are interventions to prevent or delay the onset of myopia, slow its progression, and to address the problem of mechanical instability of highly myopic eyes. Although treatment approaches are growing in number, evidence of treatment efficacy is variable. This article reviews research behind such interventions under four categories: optical, pharmacological, environmental (behavioral), and surgical. In summarizing the evidence of efficacy, results from randomized controlled trials have been given most weight, although such data are very limited for some treatments. The overall conclusion of this review is that there are multiple avenues for intervention worthy of exploration in all categories, although in the case of optical, pharmacological, and behavioral interventions for preventing or slowing progression of myopia, treatment efficacy at an individual level appears quite variable, with no one treatment being 100% effective in all patients. Further research is critical to understanding the factors underlying such variability and underlying mechanisms, to guide recommendations for combined treatments. There is also room for research into novel treatment options.

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Section: Spectaclesmentioning

confidence: 99%

IMI – Interventions for Controlling Myopia Onset and Progression Report

Wildsoet

Chia

Cho

et al. 2019

Invest. Ophthalmol. Vis. Sci.

252

275

View full text Add to dashboard Cite

show abstract

“…13,15 The results suggest that the effectiveness of myopia regulation with lenses of this type 13,15 cannot be exclusively assigned to peripheral myopic defocus or peripheral astigmatic defocus and other factors may be involved, including changes in both the accommodative activity of the eye and the focusing properties at the foveal area. 50,51 Recently, Smith et al suggested that the efficacy of bifocal concentric addition designs used in myopia progression trials 13 might be explained by a certain effect of peripheral myopic defocus in addition to other potential mechanisms affecting the foveal vision. Although our methodology does not support such an assumption, we have to recognize that due to the sudden power changes between distance and near zones in these MFCL, measuring methods such as autorefractometry or even aberrometry might not be sensitive enough to detect such a hypothetical peripheral myopic defocus, and it is a limitation of this study.…”

Section: Discussionmentioning

confidence: 99%

Astigmatic Peripheral Defocus with Different Contact Lenses: Review and Meta-Analysis

Queirós

Lopes-Ferreira

González-Meijóme

2016

Current Eye Research

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“…Rigid gas‐permeable (RGP) lenses for vision correction have become unpopular and only four per cent of infections involved patients with RGP lenses. Ortho‐K utilises reverse geometry RGP lens design to modify the corneal shape when worn during sleep, to reduce myopia and, over time, decrease myopia progression in children . There has been much publicity attached to case reports of incidences of microbial keratitis associated with ortho‐K, but the risk of infection, as demonstrated in several large‐scale studies, is actually considerably lower (13.9 per 10,000 patient‐years) than extended wear of soft contact lenses (19.5 per 10,000 patient‐years) and silicone‐hydrogel extended wear (25.4 per 10,000 patient‐years) …”

Section: Use Of Contact Lensesmentioning

confidence: 99%

Disturbing the balance: effect of contact lens use on the ocular proteome and microbiome

Boost

Cho

Wang

2017

Clinical and Experimental Optometry

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Contact lens wear is a popular, convenient and effective method for vision correction. In recent years, contact lens practice has expanded to include new paradigms, including orthokeratology; however, their use is not entirely without risk, as the incidence of infection has consistently been reported to be higher in contact lens wearers. The explanations for this increased susceptibility have largely focused on physical damage, especially to the cornea, due to a combination of hypoxia, mechanical trauma, deposits and solution cytotoxicity, as well as poor compliance with care routines leading to introduction of pathogens into the ocular environment. However, in recent years, with the increasing availability and reduced cost of molecular techniques, the ocular environment has received greater attention with in‐depth studies of proteins and other components. Numerous proteins were found to be present in the tears and their functions and interactions indicate that the tears are far more complex than formerly presumed. In addition, the concept of a sterile or limited microbial population on the ocular surface has been challenged by analysis of the microbiome. Ocular microbiome was not considered as one of the key sites for the Human Microbiome Project, as it was thought to be limited compared to other body sites. This was proven to be fallacious, as a wide variety of micro‐organisms were identified in the analyses of human tears. Thus, the ocular environment is now recognised to be more complicated and interference with this ecological balance may lead to adverse effects. The use of contact lenses clearly changes the situation at the ocular surface, which may result in consequences which disturb the balance in the healthy eye.

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Stabilization in early adult-onset myopia with corneal refractive therapy

Cited by 17 publications

References 30 publications

IMI – Interventions for Controlling Myopia Onset and Progression Report

IMI – Interventions for Controlling Myopia Onset and Progression Report

Astigmatic Peripheral Defocus with Different Contact Lenses: Review and Meta-Analysis

Disturbing the balance: effect of contact lens use on the ocular proteome and microbiome

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