Stability studies of collagen-based microspheres with Calendula officinalis flower extract

Kozłowska, Justyna; Stachowiak, Natalia; Prus, Weronika

doi:10.1016/j.polymdegradstab.2019.03.015

Cited by 23 publications

(13 citation statements)

References 35 publications

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“…After 3 min of incubation, 300 µL of saturated Na 2 CO 3 solution was added to the above mixture, and the final solution was kept at 40 °C until a characteristic blue color was obtained (i.e., approx. for 30 min) [ 16 ]. The absorbance was measured spectrophotometrically at 725 nm.…”

Section: Methodsmentioning

confidence: 99%

Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid

Michalska‐Sionkowska

Warżyńska

Kaczmarek-Szczepańska

et al. 2021

Polymers

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Hydrogels based on collagen/β-glucan crosslinked with tannic acid were obtained by neutralization using dialysis. The presence of tannic acid allowed obtaining stable hydrogel materials with better mechanical properties. Tannic acid was released from matrices gradually and not rapidly. The antioxidant properties of the obtained hydrogels increased over the course of their incubation in culture media and were dependent on the concentration of tannic acid in the matrices. The obtained materials influenced dehydrogenase activity and the ATP level of pathogens. Additionally, the materials’ extracts improved the HaCaT cells’ viability. Therefore, the obtained hydrogels seem to be promising biocompatible materials which display antimicrobial properties.

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Section: Methodsmentioning

confidence: 99%

Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid

Michalska‐Sionkowska

Warżyńska

Kaczmarek-Szczepańska

et al. 2021

Polymers

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“…EDC-NHS enhances collagen stability to enzymes (for example collagenase). Furthermore, collagen stabilized by EDC-NHS in proper form is used as a specific system that delivers adequate ingredients [ 84 ]. Collagen cross-linked using EDC-NHS showed improved mechanical properties and good biocompatibility [ 85 ].…”

Section: Collagen Modification By Cross-linkingmentioning

confidence: 99%

Collagen Based Materials in Cosmetic Applications: A Review

et al. 2020

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This review provides a report on properties and recent advances in the application of collagen in cosmetics. Collagen is a structural protein found in animal organisms where it provides for the fundamental structural support. Most commonly it is extracted from mammalian and fish skin. Collagen has attracted significant academic interest as well as the attention of the cosmetic industry due to its interesting properties that include being a natural humectant and moisturizer for the skin. This review paper covers the biosynthesis of collagen, the sources of collagen used in the cosmetic industry, and the role played by this protein in cosmetics. Future aspects regarding applications of collagen-based materials in cosmetics have also been mentioned.

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“…The gelatin microspheres were obtained using the method detailed in our previous paper with some modifications [25]. Briefly, microspheres were produced from 20% (w/w) aqueous gelatin solution.…”

Section: Preparation Of Gelatin Microspheresmentioning

confidence: 99%

“…The biopolymers used in this work were gelatin-to obtain microspheres, as well as sodium alginate and starch-to obtain the polymer matrices. We have prepared the gelatin microspheres tested in our laboratory previously, which were at first incorporated into porous three-dimensional matrices made from collagen, gelatin, and hydroxyethyl cellulose [25][26][27]. This time, we decided to investigate how these types of microspheres will work after incorporation into polymer thin films.…”

Section: Introductionmentioning

confidence: 99%

Controlling the Skin Barrier Quality through the Application of Polymeric Films Containing Microspheres with Encapsulated Plant Extract

Kozłowska

Tylkowski²,

Stachowiak

et al. 2020

Processes

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Human skin has protective functions and it is a barrier that protects the interior of the body from harmful environmental factors and pathogen penetration. An important role of the skin is also to prevent the loss of water from the body and if the skin barrier is damaged, the amount of water emitted from the internal environment is increased. Therefore, it is crucial to recovery and maintenance of epidermal barrier integrity. The aim of the current work was to encapsulate Calendula officinalis flower extract in gelatin microspheres and then incorporation microspheres into thin polymeric films made from sodium alginate or mixture of sodium alginate and starch. Such materials may find applications in the cosmetic field for example in the preparation of masks for skin, according to the Calendula officinalis flower extract wide influence on skin condition. Thus, the release profile of this extract from the materials was tested under conditions corresponding to the skin (pH 5.4, 37 °C). The mechanical properties, surface free energy, and moisture content of obtained films were measured. To determine the barrier quality of the stratum corneum, transepidermal water loss (TEWL) and skin color measurements were performed. The loaded microspheres were successfully incorporated into polymeric films without affecting its useful properties. Although the values of Young’s modulus and the moisture content were decreased after film modification by microspheres addition, the skin parameters were much better after application of films with microspheres. The results confirmed that obtained materials can be potentially used in cosmetics to improve the skin barrier quality.

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Stability studies of collagen-based microspheres with Calendula officinalis flower extract

Cited by 23 publications

References 35 publications

Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid

Characterization of Collagen/Beta Glucan Hydrogels Crosslinked with Tannic Acid

Collagen Based Materials in Cosmetic Applications: A Review

Controlling the Skin Barrier Quality through the Application of Polymeric Films Containing Microspheres with Encapsulated Plant Extract

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