Stability of Salvia fruticosa Mill. polyphenols and antioxidant activity  in a citrate-based natural deep eutectic solvent

Grigorakis, Spyros; Halahlah, Abedalghani; Makris, Dmitris

doi:10.36547/nbc.v19i2.775

Cited by 2 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Likewise, polyphenol extracts from Moringa oleifera leaves obtained with a glycerol/sodium acetate DES displayed drastic changes after storage for 18 days, at 50 °C [30]. On the contrary, Salvia fruticosa polyphenols in extracts obtained with a lactic acid/sodium citrate dibasic DES exhibited extraordinary stability for 30 days, at 40 °C [31].…”

Section: Polyphenolic Composition and Metabolite Stabilitymentioning

confidence: 96%

Organosolv Treatment/Polyphenol Extraction from Olive Leaves (Olea europaea L.) Using Glycerol and Glycerol-Based Deep Eutectic Solvents: Effect on Metabolite Stability

Houasni

Grigorakis

Kellil

et al. 2022

Biomass

Self Cite

View full text Add to dashboard Cite

Olive leaves (OLL) are an agri-food waste that may be regarded as a bioresource rich in bioactive polyphenolic metabolites. In this examination, simultaneous organosolv treatment/extraction of OLL polyphenols at elevated temperatures (>110 °C) has been optimized using glycerol, but also two glycerol-based deep eutectic solvents (DES). The assessment of the processes was based on the severity factor and the extraction efficiency factor. In any case, the treatment/extraction with a DES composed of glycerol and citric acid (GL-CA) was found to be the less severe and the most effective in recovering polyphenols from OLL, giving a yield of 69.35 mg gallic acid equivalents per g dry mass. On the other hand, liquid chromatography-mass spectrometry investigation revealed that extraction with either DES used provided extracts with differentiated polyphenolic profile than that obtained when water or 60% (v/v) aqueous ethanol was used as solvents. On the ground of these analysis, evidence emerged regarding hydrolysis of flavone glucosides when the treatment was performed with an alkaline DES composed of glycerol and sodium citrate. The extracts produced also exhibited diversified antioxidant activity, a fact putatively attributed to the different polyphenolic profiles. It was concluded that organosolv treatment/extraction of OLL for polyphenol recovery opens new endeavors in the valorization of this particular waste, but metabolite stability is an issue that merits profounder study.

show abstract

Section: Polyphenolic Composition and Metabolite Stabilitymentioning

confidence: 96%

Organosolv Treatment/Polyphenol Extraction from Olive Leaves (Olea europaea L.) Using Glycerol and Glycerol-Based Deep Eutectic Solvents: Effect on Metabolite Stability

Houasni

Grigorakis

Kellil

et al. 2022

Biomass

Self Cite

View full text Add to dashboard Cite

show abstract

Development of a Green Methodology for Simultaneous Extraction of Polyphenols and Pigments from Red Winemaking Solid Wastes (Pomace) Using a Novel Glycerol-Sodium Benzoate Deep Eutectic Solvent and Ultrasonication Pretreatment

et al. 2021

View full text Add to dashboard Cite

In this examination, two glycerol-based deep eutectic solvents (DESs) were tested for their efficiency in the recovery of antioxidant polyphenols and anthocyanin pigments from red grape pomace (RGP). The two DESs synthesized had sodium acetate and sodium benzoate as hydrogen bond acceptors, to test the role of the hydrogen bond acceptor polarity on the extraction performance. Furthermore, the process was enhanced by an ultrasonication pretreatment stage. After initial testing with respect to water content, ultrasonication power and liquid-to-solid ratio, the DES composed of glycerol and sodium benzoate (GL-SBz) was shown to be significantly more efficient than the one made of glycerol and sodium acetate (GL-SAc). Further optimization of the extraction with regard to time and temperature demonstrated GL-SBz to be a highly effective solvent for the production of RGP extracts rich in polyphenols including gallic acid, catechin and quercetin, and pigments including malvidin 3-O-glucoside p-coumarate and malvidin 3-O-glucoside. The extracts produced also had significantly higher antiradical activity and reducing power compared to those generated with aqueous ethanol or water. From this study, evidence emerged regarding the role of the hydrogen bond acceptor nature in the extraction efficiency of polyphenols. The process developed is proposed as a green, high-performing methodology for the production of RGP extracts with enhanced polyphenolic content and antioxidant activity.

show abstract

Stability of Salvia fruticosa Mill. polyphenols and antioxidant activity in a citrate-based natural deep eutectic solvent

Cited by 2 publications

References 13 publications

Organosolv Treatment/Polyphenol Extraction from Olive Leaves (Olea europaea L.) Using Glycerol and Glycerol-Based Deep Eutectic Solvents: Effect on Metabolite Stability

Organosolv Treatment/Polyphenol Extraction from Olive Leaves (Olea europaea L.) Using Glycerol and Glycerol-Based Deep Eutectic Solvents: Effect on Metabolite Stability

Development of a Green Methodology for Simultaneous Extraction of Polyphenols and Pigments from Red Winemaking Solid Wastes (Pomace) Using a Novel Glycerol-Sodium Benzoate Deep Eutectic Solvent and Ultrasonication Pretreatment

Contact Info

Product

Resources

About