Stability of salivary steroids: the influences of storage, food and dental care

Gröschl, Michael

doi:10.1016/s0039-128x(01)00111-8

Cited by 147 publications

(116 citation statements)

References 27 publications

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“…Neither testosterone nor cortisol was correlated with the time interval between sampling and freezing (p's > .25). In line with this, previous studies have shown that saliva samples can be mailed and/or stored at room temperature for at least 7 days and sometimes up to 4 weeks without cortisol or testosterone levels being affected (Clements & Parker, 1998;Dabbs, 1991;Garde & Hansen, 2005;Gröschl, Wagner, Rauh, & Dörr, 2001;Jensen et al, 2011;Kirschbaum & Hellhammer, 1989.…”

Section: Methodssupporting

confidence: 55%

Salivary testosterone and cortisol are jointly related to pro-environmental behavior in men

Sollberger

Bernauer

Ehlert

2015

Social Neuroscience

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Recently, cortisol has been suggested to moderate the positive relationship between testosterone and antisocial behavior. More precisely, high testosterone levels have been found to be related to aggressive or dominant behavior especially when cortisol levels were low. In the present study, we aimed to extend these findings to pro-environmental behavior as an indicator of prosocial behavior. In a first step, 147 male participants provided information on their everyday pro-environmental behavior by completing an online questionnaire on various energy-saving behaviors. In a second step, subjects provided two saliva samples for the assessment of testosterone and cortisol on two subsequent mornings after awakening. We found that testosterone was negatively related to pro-environmental behavior, but only in men with low cortisol. In conclusion, our findings provide first evidence for the joint association of testosterone and cortisol with everyday pro-environmental behavior. These results further reinforce the importance of considering interdependent hormone systems simultaneously rather than focusing on a single hormone.

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Section: Methodssupporting

confidence: 55%

Salivary testosterone and cortisol are jointly related to pro-environmental behavior in men

Sollberger

Bernauer

Ehlert

2015

Social Neuroscience

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“…Besides the fact that salivary cortisol measurement seems to be largely unaffected by the important inter-individual variation of CBG, the non-invasive manner of sampling by the patient at home in a non-stressful surrounding argues in favour of this diagnostic approach. Shipment of samples to an outpatient clinic within 24 h after sampling seems acceptable, since good stability of cortisol in saliva has been reported (21).…”

Section: Bereitgestellt Von | Universitaetsbibliothek Der Lmu Muenchenmentioning

confidence: 99%

Measurement of late-night salivary cortisol with an automated immunoassay system

Vogeser¹,

Durner²,

Seliger³

et al. 2006

Clinical Chemistry and Laboratory Medicine (CCLM)

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Background: Measurement of late-night salivary cortisol concentrations is increasingly used as a screening test in suspected Cushing's syndrome. Cortisol concentrations are typically extremely low in latenight samples and discordant assay-specific reference ranges have been reported. Therefore, the aim of our study was to assess the analytical performance of the first automated cortisol immunoassay specified for salivary measurements and to establish late-night sampling reference-range data for this test. Methods: Salivary cortisol was measured using the Roche Cobas Cortisol assay (Roche Diagnostics). Five salivary pools in different concentration ranges were used to assess the inter-assay imprecision of this test in a two-centre evaluation protocol including two reagent lots. Linearity was tested by serial dilution. Salivary samples were obtained at 23:00 h from 100 apparently healthy volunteers using a commercially available salivary sampling device (Salivette, Sarstedt). A subset of 20 samples was used for method comparison with isotope dilution liquid chromatography-tandem mass spectrometry. Results: Inter-assay coefficients of variation (ns20) between 11.6% and 40.4% were found for mean cortisol concentrations between 12.9 and 2.6 nmol/L, with an estimated functional sensitivity of approximately 5.0 nmol/L. The test also gave linear results in the lowest concentration range between 1.0 and 8.3 nmol/L. Mean late-night salivary cortisol of 5.0 nmol/L was found for healthy individuals; the absolute range was 1.4-16.7 nmol/L, and the 95th percentile was 8.9 nmol/L. Substantially lower concentrations were found with isotope dilution LC-MS/MS compared to immunoassay results (mean concentrations 1.8 and 4.4 nmol/L, respectively). Conclusions: The automated assay investigated was found to offer acceptable analytical performance in the very low concentration range required for latenight salivary cortisol, despite a very short turnaround time. Using this assay, late-night salivary

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“…Previous studies have 7 shown that progesterone in saliva samples is unaffected by storage for at 4 o C for 5 days. (Gröschl et al, 2001;Lewis 2006). The samples were collected from the participant's home by research assistants; then stored at -80 o C in the laboratory prior to analysis.…”

Section: Salivary Progesterone Collectionmentioning

confidence: 99%

A specific profile of luteal phase progesterone is associated with the development of premenstrual symptoms

Lovick

Guapo

Anselmo-Franci

et al. 2017

Psychoneuroendocrinology

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Lovick, T., Guapo, V. G., Amselmo-Franci, J. A., Loureiro, C. M., Faleiros, C. M., Del Ben, C. M., & Brandão, M. L. (2017). A specific profile of luteal phase progesterone is associated with the development of premenstrual symptoms. Psychoneuroendocrinology, 75,[86][87][88][89][90] University of Bristol -Explore Bristol Research General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms There is a consensus that the development of premenstrual dysphoric states is related to cyclical change in gonadal hormone secretion during the menstrual cycle.However, results from studies seeking to link symptom severity to luteal phase progesterone concentration have been equivocal. In the present study we evaluated not only the absolute concentrations of progesterone but also the kinetics of the change in progesterone concentration in relation to development of premenstrual symptoms during the last 10 days of the luteal phase in a population of 46 healthy young adult Brazilian women aged 18-39 years, mean 26.5±6.7 years. In participants who developed symptoms of premenstrual distress, daily saliva progesterone concentration remained stable during most of the mid-late luteal phase, before declining sharply during the last 3 days prior to onset of menstruation. In contrast, progesterone concentration in asymptomatic women underwent a gradual decline over the last 8 days prior to menstruation. Neither maximum nor minimum concentrations of progesterone in the two groups were related to the appearance or severity of premenstrual symptoms. We propose that individual differences in the kinetics of progesterone secretion and/or metabolism may confer differential susceptibility to the development of premenstrual syndrome.

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Stability of salivary steroids: the influences of storage, food and dental care

Cited by 147 publications

References 27 publications

Salivary testosterone and cortisol are jointly related to pro-environmental behavior in men

Salivary testosterone and cortisol are jointly related to pro-environmental behavior in men

Measurement of late-night salivary cortisol with an automated immunoassay system

A specific profile of luteal phase progesterone is associated with the development of premenstrual symptoms

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