Stability of generalized models for HIV-1 dynamics with impaired CTL immunity and three pathways of infection
Noura H. AlShamrani,
Reham H. Halawani,
Ahmed M. Elaiw
Abstract:Highly active antiretroviral therapy (HAART) stands out as the most effective treatment for human immunodeficiency virus type-1 (HIV-1). While total eradication is still difficult, HAART can dramatically lower the virus's plasma viral level below the detection threshold. The activation of latently infected cells is considered to be the main obstacle to the total eradication of HIV-1 infection. This study investigates the dynamic characteristics of two generalized HIV-1 infection models taking into account the … Show more
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