Stability of formal thought disorder and referential communication disturbances in schizophrenia.

Docherty, Nancy M.; Cohen, Alex S.; Nienow, Tasha M.; Dinzeo, Thomas J.; Dangelmaier, Ruth E.

doi:10.1037/0021-843x.112.3.469

Cited by 89 publications

(62 citation statements)

References 37 publications

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“…TLC ratings have been found to be less stable over time in patients than CDI ratings and more highly related to current clinical state. 42 Both CDI ratings and neuropsychological test scores have been relatively stable in patients over time and across changes in clinical state, compared with the TLC. 42,43 Lower scores on tests of sustained attention, working memory, sequencing, and conceptual sequencing were associated with higher frequencies of communication failures in speech.…”

Section: Discussionmentioning

confidence: 99%

On Identifying the Processes Underlying Schizophrenic Speech Disorder

Docherty

2011

Schizophrenia Bulletin

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Speech of people with schizophrenia is often difficult to follow. There is evidence that neuropsychological deficits associated with schizophrenia explain some of the variance in speech disorder, but its nature and causes overall are not well understood. This study rated speech samples from 60 schizophrenic outpatients for thought disorder, conceptual disorganization, linguistic structural breakdown, and communication failure. A battery of neuropsychological tests potentially relevant to coherent speech production was administered, and associations between these variables and the speech measures were assessed. Consistent with previous research, the measure of functional effect, communication failure, was more highly associated with neuropsychological test performance than were the measures of putative cause: thought disorder, conceptual disorganization, or linguistic structural breakdown. Performance on tests of attention, immediate memory, working memory, organizational sequencing, and conceptual sequencing all were significantly related to the frequency of communication failures in the speech. In hierarchical regression, attention, working memory, and conceptual sequencing each contributed significantly and together explained 29% of the variance. Some other potential contributors to test in future research include auditory attention, internal source memory, emotional disturbances, and social cognitive deficits.

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Section: Discussionmentioning

confidence: 99%

On Identifying the Processes Underlying Schizophrenic Speech Disorder

Docherty

2011

Schizophrenia Bulletin

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“…Structural unclarities and wrong words were especially common in schizophrenia; ambiguous words were especially common in mania. Docherty et al (2003) found that, in schizophrenia, many of these disturbances (all except vague reference) are btraitlike,Q stable over time, and relatively uncorrelated with formal thought disorder or severity of psychotic symptoms. This is particularly intriguing because poor cohesion in speech has been thought to be a prodromal or subclinical symptom in those with a genetic predisposition to schizophrenia (Wynne et al (1977), Goldstein (1985), Docherty (1995)).…”

Section: Cohesion and Referencementioning

confidence: 99%

Schizophrenia and the structure of language: The linguist's view

Covington

Brown

et al. 2005

Schizophrenia Research

295

223

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Patients with schizophrenia often display unusual language impairments. This is a wide ranging critical review of the literature on language in schizophrenia since the 19th century. We survey schizophrenic language level by level, from phonetics through phonology, morphology, syntax, semantics, and pragmatics.There are at least two kinds of impairment (perhaps not fully distinct): thought disorder, or failure to maintain a discourse plan, and schizophasia, comprising various dysphasia-like impairments such as clanging, neologism, and unintelligible utterances.Thought disorder appears to be primarily a disruption of executive function and pragmatics, perhaps with impairment of the syntax-semantics interface; schizophasia involves disruption at other levels. Phonetics is also often abnormal (manifesting as flat intonation or unusual voice quality), but phonological structure, morphology, and syntax are normal or nearly so (some syntactic impairments have been demonstrated). Access to the lexicon is clearly impaired, manifesting as stilted speech, word approximation, and neologism. Clanging (glossomania) is straightforwardly explainable as distraction by self-monitoring.Recent research has begun to relate schizophrenia, which is partly genetic, to the genetic endowment that makes human language possible. D

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“…Thought disorder has been considered to be a core feature of schizophrenia (Bleuler, 1950) and has been described as either a positive symptom (Andreasen and Olsen, 1982) or as part of the disorganization syndrome (Liddle, 1987). Longitudinal studies have found that the severity of thought disorder in schizophrenia is moderately stable typically Asarnow and MacCrimmon, 1982;Docherty et al, 2003) of illness. However, even in relatively stable outpatients, the frequency of thinking disturbance has been found to be greater among patients with schizophrenia than nonpsychiatric controls (Sponheim et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Neurocognitive and social cognitive correlates of formal thought disorder in schizophrenia patients

Subotnik

Nuechterlein

Green

et al. 2006

Schizophrenia Research

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The neurocognitive and social cognitive correlates of two types of formal thought disorder (i.e., bizarre-idiosyncratic and concrete thinking) were examined in 47 stable outpatients with schizophrenia. Both types of thinking disturbance were related to impairments in verbal learning, intrusions in verbal memory, immediate auditory memory, sustained attention, and social schema knowledge. Distractibility during an immediate memory task was associated with more frequent bizarre verbalizations but not concreteness. Impaired verbal learning rate and intrusions in verbal memory independently contributed to the prediction of bizarre responses, whereas intrusions in verbal memory and impaired immediate memory independently contributed to concrete thinking. This pattern of findings is consistent with the view that neurocognitive and, possibly, social cognitive deficits underlie these two aspects of formal thinking disturbance in schizophrenia. D

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Stability of formal thought disorder and referential communication disturbances in schizophrenia.

Cited by 89 publications

References 37 publications

On Identifying the Processes Underlying Schizophrenic Speech Disorder

On Identifying the Processes Underlying Schizophrenic Speech Disorder

Schizophrenia and the structure of language: The linguist's view

Neurocognitive and social cognitive correlates of formal thought disorder in schizophrenia patients

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