Stability of dietary ascorbic acid and the effect of supplementation on reproductive performance of broiler breeder chickens

Creel, Linda H.; Maurice, D. V.; Lightsey, S. F.; Grimes, L. W.

doi:10.1080/713655016

Cited by 15 publications

(10 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since ascorbic acid is synthesised in the chicken body and not found in the egg its direct role in internal egg quality is questionable. The results of Creel et al. (2001) did not provide evidence of a beneficial reproductive response to the inclusion of ascorbic acid in commercial broiler breeder diets.…”

Section: Antioxidant Defences Of the Developing Embryomentioning

confidence: 72%

Antioxidant systems in chick embryo development. Part 1. Vitamin E, carotenoids and selenium

2016

View full text Add to dashboard Cite

Chick viability is known to be an important factor determining profitability of the poultry industry. Chick embryo tissues contain a high proportion of highly polyunsaturated fatty acids in the lipid fraction and therefore need antioxidant defence. The antioxidant system of the developing embryo and newly hatched chick includes the antioxidant enzymes (superoxide dismutase, glutathione peroxidase, catalase), water-soluble antioxidants (ascorbic acid, taurine, carnitine, glutathione, etc.), fat-soluble antioxidants (vitamin E, carotenoids, coenzyme Q) as well as selenium (Se). In fact, the high levels of endogenous antioxidants within the egg and embryonic tissues can clearly serve as a major adaptive mechanism for the protection of the tissue during the oxidative stress experienced at hatching. It has been shown that among different nutrients in the maternal diet which could significantly affect chick embryo development and their viability in the early posthatch life, natural antioxidants have been suggested to play a central role. Our data indicate that increased supplementation of the maternal diet can substantially increase concentrations of vitamin E, carotenoids (especially canthaxanthin) and Se in developing chick tissues and significantly decrease susceptibility to lipid peroxidation being effective nutritional tools to deal with various commercial stresses in poultry production.

show abstract

Section: Antioxidant Defences Of the Developing Embryomentioning

confidence: 72%

Antioxidant systems in chick embryo development. Part 1. Vitamin E, carotenoids and selenium

2016

View full text Add to dashboard Cite

show abstract

“…Dietary supplementation with AA improved the production performance and immunity status of old laying hens (72 weeks old) subjected to severe heat stress conditions [ 10 ]. However, some results have shown that the supplementation of AA was found to have no effect on the production performance of laying hens (31 weeks old) under oxidant stress [ 11 ] and broiler breeder chickens [ 12 ]. Such inconsistent results regarding AA supplementation prompted an examination of the changes in distribution and transportation of AA in different tissues and GLO enzyme activity in poultry of different ages.…”

Section: Introductionmentioning

confidence: 99%

Ascorbic acid synthesis and transportation capacity in old laying hens and the effects of dietary supplementation with ascorbic acid

Gan

Fan

Nie

et al. 2018

J Animal Sci Biotechnol

View full text Add to dashboard Cite

BackgroundLaying hens over 75 weeks of age commonly show great declines in immunity and production performance. It is unclear whether these declines can be relieved by supplementing with ascorbic acid (AA) in feed. Two trials were conducted to investigate the synthesis and metabolism of AA in layers of different ages and the effects of dietary supplemental AA on the performance and the immune and antioxidant statuses of 78 weeks old hens.MethodsIn Exp. 1, equal numbers (24 hens) of 35 weeks old (Young) and 75 weeks old (Old) layers were fed the same diet without AA supplementation for 4 weeks. In Exp. 2, 360 healthy 78 weeks old laying hens were randomly assigned to 4 treatments (basal diet supplemented with 0, 0.25, 0.5, or 1 g AA/kg diet) in an 8-week feeding trial.ResultsThe old hens tended to have decreased L-gulonolactone oxidase (GLO) synthase activity in the kidney and liver than that of the young hens (P = 0.07 and P = 0.05, respectively). Compared with the young hens, the old hens had lower hepatic antioxidant capacity allowing for the lower thioredoxin (TXN), thioredoxin reductase (TXNR) and cytochrome b5 reductase (CYB5R) gene expression (P < 0.05), whereas increased sodium-dependent vitamin C transporter (SVCT) 1 expression levels in the ileum and kidney and enhanced splenic and hepatic AA concentrations (P < 0.05). Dietary supplementation with AA significantly decreased GLO enzyme activity but increased splenic AA concentration and anti-bovine serum albumin IgG levels (P < 0.05) and tended to increase CD4+ T lymphocyte numbers (P = 0.06) in serum. Supplementation of 0.25 g AA/kg diet significantly increased hepatic total antioxidant capacity (T-AOC, P < 0.05) relative to the control group.ConclusionsLaying hens could synthesize AA in both the kidney and the liver, though the GLO enzyme activities were 100 times greater in kidneys than in livers. The old laying hens had greater absorption and reabsorption capacity and higher AA retention in some tissues that did the young hens. Dietary supplementation of AA can improve the health of old layers by enhancing immunity and antioxidant capacity.

show abstract

“…Tissue samples were homogenized in 5% cold trichloroacetic acid for about 10 s using a Polytron (Model MR 2100, Kinematica AG, Switzerland) homogenizer set at 22. The homogenate was centrifuged at 16 000 g for 1 min and the supernatant used to measure ascorbic acid ( Creel et al, 2001). Tissue samples were processed and assayed within 3 weeks storage at −20 °C.…”

Section: Biochemical Measurementsmentioning

confidence: 99%

“…The responses of poultry to supplemental AsA have been inconsistent ( Scott , 1975; Pardue and Thaxton , 1986; Keshavarz , 1996; Okoye et al, 1998; Chen and Balnave , 2001; Creel et al, 2001). The equivocal responses may be ascribed to dietary and/or environmental factors that influence ascorbate metabolism and were confounded in the experiments.…”

Section: Introductionmentioning

confidence: 99%

Factors affecting ascorbic acid biosynthesis in chickens: III. Effect of dietary fluoride on l‐gulonolactone oxidase activity and tissue ascorbic acid (AsA) concentration

Maurice¹,

Lightsey²,

Abudabos³

et al. 2002

Animal Physiology Nutrition

View full text Add to dashboard Cite

The inconsistent beneficial responses to dietary ascorbic acid (AsA) may be due to dietary factors that alter biosynthesis or tissue turnover of AsA. It has been suggested on the basis of altered tissue AsA that dietary fluoride is a determinant of biosynthesis in chickens. Fluoride may enter the food chain of poultry via industrial contamination, feed ingredients and drinking water. The goal of this study was to ascertain whether dietary fluoride at 300 mg/kg influences l-gulonolactone oxidase (GLO) activity in commercial meat-type chickens. The experimental diet was fed from day-old to 3 weeks and responses measured. Growth and feed conversion were not affected by fluoride in the diet. Dietary fluoride neither inhibited nor enhanced GLO activity nor did it increase or decrease AsA concentration in plasma, liver, kidney, adrenal gland and muscle (pectoralis major). Tissue AsA concentration in ascending order was adrenal > liver > kidney > pectoralis major > plasma. The results are consistent with that reported for the rat and calculations based on the results eliminate fluorine contamination for the inconsistent responses of immature chickens to dietary AsA.

show abstract

Stability of dietary ascorbic acid and the effect of supplementation on reproductive performance of broiler breeder chickens

Cited by 15 publications

References 32 publications

Antioxidant systems in chick embryo development. Part 1. Vitamin E, carotenoids and selenium

Antioxidant systems in chick embryo development. Part 1. Vitamin E, carotenoids and selenium

Ascorbic acid synthesis and transportation capacity in old laying hens and the effects of dietary supplementation with ascorbic acid

Factors affecting ascorbic acid biosynthesis in chickens: III. Effect of dietary fluoride on l‐gulonolactone oxidase activity and tissue ascorbic acid (AsA) concentration

Contact Info

Product

Resources

About