Stability of aqueous TiO2 suspensions: influence of ethanol

Lebrette, Séverine; Pagnoux, Cécile; Abelard, Peter

doi:10.1016/j.jcis.2004.07.033

Cited by 51 publications

(37 citation statements)

References 17 publications

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“…In the case of ethanolic aqueous solutions, alcohol molecules firstly fill the voids of the hydrogen-bond network of the water structure and "fortify" the structure due to the hydrogen bonds between the hydroxyl oxygen of alcohol and water. 34 This explains the increase of the viscosity of formulations containing ethanol. Although UDV formulations were suitable for topical application, other dosage forms could be considered depending on the application site.…”

Section: Results and Discussion Characterization Of Udv Formulationsmentioning

confidence: 97%

Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes

Ascenso¹,

Raposo²,

Batista³

et al. 2015

IJN

256

150

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Ultradeformable vesicles (UDV) have recently become a promising tool for the development of improved and innovative dermal and transdermal therapies. The aim of this work was to study three related UDV: transfersomes, ethosomes, and transethosomes for the incorporation of actives of distinct polarities, namely, vitamin E and caffeine, and to evaluate the effect of the carrier on skin permeation and penetration. These actives were incorporated in UDV formulations further characterized for vesicles imaging by transmission electron microscopy; mean vesicle size and polydispersity index by photon correlation spectroscopy; zeta potential by laser-Doppler anemometry; deformability by pressure-driven transport; and incorporation efficiency (IE) after actives quantification by high-performance liquid chromatography. Topical delivery studies were performed in order to compare UDV formulations regarding the release, skin permeation, and penetration profiles. All UDV formulations showed size values within the expected range, except transethosomes prepared by “transfersomal method”, for which size was smaller than 100 nm in contrast to that obtained for vesicles prepared by “ethosomal method”. Zeta potential was negative and higher for formulations containing sodium cholate. The IE was much higher for vitamin E- than caffeine-loaded UDV as expected. For flux measurements, the following order was obtained: transethosomes (TE) > ethosomes (E) ≥ transfersomes (T). This result was consistent with the release and skin penetration profiles for Vitamin E-loaded UDV. However, the releasing results were totally the opposite for caffeine-loaded UDV, which might be explained by the solubility and thermodynamic activity of this active in each formulation instead of the UDV deformability attending to the higher non-incorporated fraction of caffeine. Anyway, a high skin penetration and permeation for all caffeine-loaded UDV were obtained. Transethosomes were more deformable than ethosomes and transfersomes due to the presence of both ethanol and surfactant in their composition. All these UDV were suitable for a deeper skin penetration, especially transethosomes.

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Section: Results and Discussion Characterization Of Udv Formulationsmentioning

confidence: 97%

Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes

Ascenso¹,

Raposo²,

Batista³

et al. 2015

IJN

256

150

View full text Add to dashboard Cite

show abstract

“…Thus, the major part of the particles surface is not occupied by dispersant molecules, and additional surface sites are still available for occupation. Surface coverage by the dispersant is limited mainly by the size and rigidity of the benzenic ring and mutual repulsions between adsorbed molecules [28]. Fig.…”

Section: Resultsmentioning

confidence: 99%

A study on the aqueous dispersion mechanism of CuO powders using Tiron

Guedes

Ferreira

Ferro

2009

Journal of Colloid and Interface Science

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“…EPD is achieved via the motion of charged particles towards an electrode under the influence of an electric field and requires the use of stable suspensions. Bath compositions for EPD included various additives, which provided stabilization and charging of inorganic particles in the bulk of suspensions [8][9][10][11][12]. Deposit formation was achieved via coagulation and precipitation of the particles at the electrode surface.…”

Section: Introductionmentioning

confidence: 99%